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Incidence, risk factors, microbiology of venous catheter associated bloodstream infections--a prospective study from a tertiary care hospital.静脉导管相关血流感染的发病率、危险因素及微生物学——一项来自三级医院的前瞻性研究
Indian J Med Microbiol. 2015 Apr-Jun;33(2):248-54. doi: 10.4103/0255-0857.153572.
2
Non-albicans Candida Infection: An Emerging Threat.非白念珠菌感染:一种新出现的威胁。
Interdiscip Perspect Infect Dis. 2014;2014:615958. doi: 10.1155/2014/615958. Epub 2014 Oct 22.
3
Diagnosis of ventilator-associated pneumonia: comparison between ante-mortem and post-mortem cultures in trauma patients.呼吸机相关性肺炎的诊断:创伤患者生前与死后培养结果的比较
Indian J Med Microbiol. 2014 Jul-Sep;32(3):294-300. doi: 10.4103/0255-0857.136572.
4
Virulence Factors Contributing to Pathogenicity of Candida tropicalis and Its Antifungal Susceptibility Profile.热带假丝酵母菌致病的毒力因子及其抗真菌药敏谱
Int J Microbiol. 2014;2014:456878. doi: 10.1155/2014/456878. Epub 2014 Apr 2.
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Intravascular catheter related infections and antimicrobial susceptibility pattern of isolated bacteria in a tertiary care hospital of Bangladesh.孟加拉国一家三级护理医院中血管内导管相关感染及分离细菌的抗菌药敏模式
Indian J Med Microbiol. 2014 Jan-Mar;32(1):68-71. doi: 10.4103/0255-0857.124321.
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Candiduria in catheterized intensive care unit patients: emerging microbiological trends.重症监护病房留置导尿管患者的念珠菌尿症:新出现的微生物学趋势
Indian J Pathol Microbiol. 2011 Jul-Sep;54(3):552-5. doi: 10.4103/0377-4929.85091.
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Candida glabrata, Candida parapsilosis and Candida tropicalis: biology, epidemiology, pathogenicity and antifungal resistance.光滑念珠菌、近平滑念珠菌和热带念珠菌:生物学、流行病学、致病性和抗真菌耐药性。
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Candida urinary tract infections--epidemiology, pathogenesis, diagnosis, and treatment: executive summary.念珠菌性尿路感染——流行病学、发病机制、诊断和治疗:执行摘要。
Clin Infect Dis. 2011 May;52 Suppl 6:S429-32. doi: 10.1093/cid/cir108.
9
Changes in the incidence of candidaemia during 2000-2008 in a tertiary medical centre in northern Taiwan.2000-2008 年台湾北部一家三级医疗中心念珠菌血症发病率的变化。
J Hosp Infect. 2011 May;78(1):50-3. doi: 10.1016/j.jhin.2010.12.007. Epub 2011 Feb 12.
10
Surveillance of device-associated infections at a teaching hospital in rural Gujarat--India.印度古吉拉特邦农村地区一家教学医院的设备相关感染监测
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印度一家农村三级护理教学医院中与医疗器械相关的念珠菌感染

Medical Device-Associated Candida Infections in a Rural Tertiary Care Teaching Hospital of India.

作者信息

Deorukhkar Sachin C, Saini Santosh

机构信息

Department of Microbiology, Rural Medical College, Pravara Institute of Medical Sciences (Deemed University), Loni, Maharashtra 413736, India.

出版信息

Interdiscip Perspect Infect Dis. 2016;2016:1854673. doi: 10.1155/2016/1854673. Epub 2016 Jan 24.

DOI:10.1155/2016/1854673
PMID:26904115
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4745319/
Abstract

Health care associated infections (HCAIs) add incrementally to the morbidity, mortality, and cost expected of the patient's underlying diseases alone. Approximately, about half all cases of HCAIs are associated with medical devices. As Candida medical device-associated infection is highly drug resistant and can lead to serious life-threatening complications, there is a need of continuous surveillance of these infections to initiate preventive and corrective measures. The present study was conducted at a rural tertiary care hospital of India with an aim to evaluate the rate of medical device-associated Candida infections. Three commonly encountered medical device-associated infections (MDAI), catheter-associated urinary tract infection (CA-UTI), intravascular catheter-related blood stream infections (CR-BSI), and ventilator-associated pneumonia (VAP), were targeted. The overall rate of MDAI in our hospital was 2.1 per 1000 device days. The rate of Candida related CA-UTI and CR-BSI was noted as 1.0 and 0.3, respectively. Untiring efforts taken by team members of Hospital Acquired Infection Control Committee along with maintenance of meticulous hygiene of the hospital and wards may explain the low MDAI rates in our institute. The present surveillance helped us for systematic generation of institutional data regarding MDAI with special reference to role of Candida spp.

摘要

医疗保健相关感染(HCAIs)会额外增加仅由患者基础疾病所预期的发病率、死亡率和成本。大约所有HCAIs病例中有一半与医疗器械有关。由于念珠菌医疗器械相关感染具有高度耐药性,并可导致严重的危及生命的并发症,因此需要持续监测这些感染,以便采取预防和纠正措施。本研究在印度一家农村三级护理医院进行,旨在评估医疗器械相关念珠菌感染的发生率。针对三种常见的医疗器械相关感染(MDAI),即导管相关尿路感染(CA-UTI)、血管内导管相关血流感染(CR-BSI)和呼吸机相关性肺炎(VAP)。我院MDAI的总体发生率为每1000个器械日2.1例。念珠菌相关CA-UTI和CR-BSI的发生率分别为1.0和0.3。医院感染控制委员会的团队成员不懈努力,以及保持医院和病房的细致卫生,可能解释了我院较低的MDAI发生率。本次监测有助于我们系统地生成有关MDAI的机构数据,特别是关于念珠菌属的作用。