Hu Yan, Liu Yalan, Shi Hongcheng
Department of Nuclear Medicine.
Institute of Nuclear Medicine.
Medicine (Baltimore). 2018 Mar;97(12):e9939. doi: 10.1097/MD.0000000000009939.
Castleman disease is a rare lymphoproliferative disorder which etiology is unknown. It is divided into 2 subtypes: the plasma cell variant and the hyaline vascular variant. The most common site is the hilum of the lungs and mediastinum. Castleman disease is often ignored by clinicians because of not frequently encountering in clinical and the lower uptake of F-FDG. Here, we report a case of hepatocellular carcinoma accompanied by Castleman disease in the hilum of the liver, which was misdiagnosed as the lymph node metastasis in F-FDG PET/CT imaging.
A 63-year-old male with chief complaint of acratia and poor appetite for 2 weeks.
Hepatocellular carcinoma accompanied by Castleman disease in the hilum of liver.
Right hemihepatectomy and hilar lymph node dissection was performed and preventative transcatheter arterial chemoembolization therapy was given after the surgery.
The case had multiple systemic metastasis due to tumor progression.
Castleman disease is a benign and rare lympholiferative disease, and easy to be ignored in clinical. The case of hepatic carcinoma with Castleman disease in the hilum of liver has never been reported before. Here, we report it and hope it provides a differential diagnosis for clinicians in the following similar cases.
Castleman病是一种病因不明的罕见淋巴增生性疾病。它分为两种亚型：浆细胞型和透明血管型。最常见的部位是肺门和纵隔。由于临床中不常遇到且F-FDG摄取较低，Castleman病常被临床医生忽视。在此，我们报告一例肝门部肝细胞癌合并Castleman病的病例，该病例在F-FDG PET/CT成像中被误诊为淋巴结转移。
一名63岁男性，主诉乏力、食欲减退2周。
肝门部肝细胞癌合并Castleman病。
行右半肝切除术及肝门淋巴结清扫术，术后给予预防性经动脉化疗栓塞治疗。
该病例因肿瘤进展出现多处全身转移。
Castleman病是一种良性罕见的淋巴增生性疾病，在临床中易被忽视。肝门部肝细胞癌合并Castleman病的病例此前未见报道。在此，我们予以报道，希望为临床医生在后续类似病例中提供鉴别诊断依据。
