Edgell Heather, Stickland Michael K, MacLean Joanna E
aWomen and Children's Health Research Institute Departments of bMedicine cPediatrics, University of Alberta, Edmonton, Alberta dSchool of Kinesiology and Health Sciences, York University, Toronto, Ontario, Canada.
Blood Press Monit. 2016 Jun;21(3):192-5. doi: 10.1097/MBP.0000000000000183.
The standard measurement of pulse wave velocity (PWV) is restricted by the need for simultaneous tonometry measurements requiring two technicians and expensive equipment, limiting this technique to well-resourced settings. In this preliminary study, we compared a simplified method of pulse wave detection from the finger and toe to pulse wave detection from the carotid and radial arteries using applanation tonometry in children and young adults. We hypothesized that the simplified method of PWV measurement would strongly correlate with the standard measurement in different age groups and oxygen conditions. Participants included (a) boys and girls aged 8-12 years and (b) men and women aged 18-40 years. Participants rested supine while carotid and radial artery pulse waves were measured using applanation tonometry and finger and toe pulse waves were simultaneously collected using a Finometer Midi and a piezo-electric pulse transducer, respectively. These measurements were repeated under hypoxic conditions. Finger-toe PWV measurements were strongly correlated to carotid-radial PWV in adults (R=0.58; P=0.011), but not in children (R=0.056; P=0.610). Finger-toe PWV was sensitive enough to show increases in PWV with age (P<0.0001) and hypoxia in children (P<0.0001) and adults (P=0.003). These results indicate that the simplified measurement of finger-toe PWV strongly correlates with the standard measurement of carotid-radial PWV in adults, but not in children. However, finger-toe PWV can be used in either population to determine changes with hypoxia.
脉搏波速度（PWV）的标准测量方法受到限制，因为需要同时进行眼压测量，这需要两名技术人员和昂贵的设备，使得该技术只能在资源充足的环境中使用。在这项初步研究中，我们比较了一种从手指和脚趾检测脉搏波的简化方法与在儿童和年轻人中使用压平眼压计从颈动脉和桡动脉检测脉搏波的方法。我们假设，PWV测量的简化方法在不同年龄组和氧气条件下与标准测量方法有很强的相关性。参与者包括（a）8至12岁的男孩和女孩，以及（b）18至40岁的男性和女性。参与者仰卧休息，使用压平眼压计测量颈动脉和桡动脉的脉搏波，同时分别使用Finometer Midi和压电脉冲传感器收集手指和脚趾的脉搏波。这些测量在低氧条件下重复进行。手指到脚趾的PWV测量在成年人中与颈动脉到桡动脉的PWV密切相关（R=0.58；P=0.011），但在儿童中不相关（R=0.056；P=0.610）。手指到脚趾的PWV足够敏感，能够显示出儿童（P<0.0001）和成年人（P<0.0001）中PWV随年龄增长（P<0.0001）以及低氧状态（儿童中P<0.0001，成年人中P=0.003）的增加。这些结果表明，手指到脚趾PWV的简化测量在成年人中与颈动脉到桡动脉PWV的标准测量密切相关，但在儿童中并非如此。然而，手指到脚趾的PWV可用于任何人群以确定低氧状态下的变化。
