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记忆的计算原理。

Computational principles of memory.

机构信息

Center for Learning and Memory and Department of Neuroscience, The University of Texas at Austin, Austin, Texas, USA.

出版信息

Nat Neurosci. 2016 Mar;19(3):394-403. doi: 10.1038/nn.4237.

DOI:10.1038/nn.4237
PMID:26906506
Abstract

The ability to store and later use information is essential for a variety of adaptive behaviors, including integration, learning, generalization, prediction and inference. In this Review, we survey theoretical principles that can allow the brain to construct persistent states for memory. We identify requirements that a memory system must satisfy and analyze existing models and hypothesized biological substrates in light of these requirements. We also highlight open questions, theoretical puzzles and problems shared with computer science and information theory.

摘要

存储和后续使用信息的能力对于各种适应性行为至关重要,包括整合、学习、泛化、预测和推理。在这篇综述中,我们调查了允许大脑构建持久记忆状态的理论原则。我们确定了记忆系统必须满足的要求,并根据这些要求分析了现有的模型和假设的生物基质。我们还强调了与计算机科学和信息论共享的开放性问题、理论难题和问题。

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1
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Elife. 2015 Nov 30;4:e10778. doi: 10.7554/eLife.10778.
2
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J Neurosci. 2015 Oct 14;35(41):13917-26. doi: 10.1523/JNEUROSCI.2916-15.2015.
3
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Proc Natl Acad Sci U S A. 2025 May 27;122(21):e2417733122. doi: 10.1073/pnas.2417733122. Epub 2025 May 19.
4
The effects of the post-delay epochs on working memory error reduction.延迟后阶段对工作记忆错误减少的影响。
PLoS Comput Biol. 2025 May 13;21(5):e1013083. doi: 10.1371/journal.pcbi.1013083. eCollection 2025 May.
5
A non-Hebbian code for episodic memory.一种用于情景记忆的非赫布编码。
Sci Adv. 2025 Feb 21;11(8):eado4112. doi: 10.1126/sciadv.ado4112.
6
A synapse-specific refractory period for plasticity at individual dendritic spines.单个树突棘可塑性的突触特异性不应期。
Proc Natl Acad Sci U S A. 2025 Jan 14;122(2):e2410433122. doi: 10.1073/pnas.2410433122. Epub 2025 Jan 7.
7
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PLoS One. 2024 Dec 4;19(12):e0314268. doi: 10.1371/journal.pone.0314268. eCollection 2024.
8
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9
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10
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4
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5
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7
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