Al-Maskari Nawal, Mohsin Jalila, Al-Maani Amal, Al-Macki Nabil, Al-Ismaili Suad
Department of Paediatric Infectious Diseases, Royal Hospital, Muscat, Oman.
Department of Microbiology, Royal Hospital, Muscat, Oman.
Sultan Qaboos Univ Med J. 2016 Feb;16(1):e86-91. doi: 10.18295/squmj.2016.16.01.016. Epub 2016 Feb 2.
The respiratory syncytial virus (RSV) usually causes a lower respiratory tract infection in affected patients. RSV has also been infrequently linked to extrapulmonary diseases in children. We report four children who had unusually severe clinical manifestations of RSV infections requiring critical care admission. These patients presented to the Royal Hospital, Muscat, Oman, in December 2013 with acute necrotising encephalopathy (ANE), acute fulminant hepatic failure with encephalopathy, pneumatoceles and croup. A unique presentation of ANE has not previously been reported in association with an RSV infection. All patients had a positive outcome and recovered fully with supportive management.
呼吸道合胞病毒（RSV）通常会使受感染患者发生下呼吸道感染。RSV也很少与儿童肺外疾病相关。我们报告了4名患有RSV感染且临床表现异常严重、需要重症监护的儿童。这些患者于2013年12月就诊于阿曼马斯喀特的皇家医院，患有急性坏死性脑病（ANE）、伴有脑病的急性暴发性肝衰竭、肺气囊和气促。此前尚未报道过ANE与RSV感染相关的独特表现。所有患者预后良好，经支持治疗后完全康复。
