呼吸道合胞病毒感染的非典型表现：病例系列
Atypical Presentations of Respiratory Syncytial Virus Infection: Case Series.
作者信息
Al-Maskari Nawal, Mohsin Jalila, Al-Maani Amal, Al-Macki Nabil, Al-Ismaili Suad
机构信息
Department of Paediatric Infectious Diseases, Royal Hospital, Muscat, Oman.
Department of Microbiology, Royal Hospital, Muscat, Oman.
出版信息
Sultan Qaboos Univ Med J. 2016 Feb;16(1):e86-91. doi: 10.18295/squmj.2016.16.01.016. Epub 2016 Feb 2.
Abstract
The respiratory syncytial virus (RSV) usually causes a lower respiratory tract infection in affected patients. RSV has also been infrequently linked to extrapulmonary diseases in children. We report four children who had unusually severe clinical manifestations of RSV infections requiring critical care admission. These patients presented to the Royal Hospital, Muscat, Oman, in December 2013 with acute necrotising encephalopathy (ANE), acute fulminant hepatic failure with encephalopathy, pneumatoceles and croup. A unique presentation of ANE has not previously been reported in association with an RSV infection. All patients had a positive outcome and recovered fully with supportive management.
摘要
呼吸道合胞病毒（RSV）通常会使受感染患者发生下呼吸道感染。RSV也很少与儿童肺外疾病相关。我们报告了4名患有RSV感染且临床表现异常严重、需要重症监护的儿童。这些患者于2013年12月就诊于阿曼马斯喀特的皇家医院，患有急性坏死性脑病（ANE）、伴有脑病的急性暴发性肝衰竭、肺气囊和气促。此前尚未报道过ANE与RSV感染相关的独特表现。所有患者预后良好，经支持治疗后完全康复。
相似文献
1
Atypical Presentations of Respiratory Syncytial Virus Infection: Case Series.呼吸道合胞病毒感染的非典型表现：病例系列
Sultan Qaboos Univ Med J. 2016 Feb;16(1):e86-91. doi: 10.18295/squmj.2016.16.01.016. Epub 2016 Feb 2.
2
Epidemiology of respiratory syncytial virus in children with lower respiratory tract infection.下呼吸道感染儿童呼吸道合胞病毒的流行病学
Acta Paediatr Taiwan. 2005 Mar-Apr;46(2):72-6.
3
Prevalence of respiratory syncytial virus infection in Italian infants hospitalized for acute lower respiratory tract infections, and association between respiratory syncytial virus infection risk factors and disease severity.意大利因急性下呼吸道感染住院的婴儿中呼吸道合胞病毒感染的患病率，以及呼吸道合胞病毒感染风险因素与疾病严重程度之间的关联。
Pediatr Pulmonol. 2002 Jun;33(6):458-65. doi: 10.1002/ppul.10047.
4
Long-term consequences of respiratory syncytial virus acute lower respiratory tract infection in early childhood in Guinea-bissau.几内亚比绍儿童早期呼吸道合胞病毒急性下呼吸道感染的长期后果
Pediatr Infect Dis J. 2006 Nov;25(11):1025-31. doi: 10.1097/01.inf.0000243214.80794.3a.
5
Acute Encephalitis and Myocarditis Associated with Respiratory Syncytial Virus Infections.与呼吸道合胞病毒感染相关的急性脑炎和心肌炎
Turk J Anaesthesiol Reanim. 2019 Aug;47(4):348-351. doi: 10.5152/TJAR.2019.52028. Epub 2019 Mar 12.
6
Respiratory syncytial virus and parainfluenza virus infections in the immunocompromised host.免疫功能低下宿主中的呼吸道合胞病毒和副流感病毒感染
Semin Respir Infect. 1995 Dec;10(4):224-31.
7
8
Expression of CTLA-4 (CD152) in peripheral blood T cells of children with influenza virus infection including encephalopathy in comparison with respiratory syncytial virus infection.与呼吸道合胞病毒感染相比，流感病毒感染（包括脑病）患儿外周血T细胞中CTLA-4（CD152）的表达情况。
Clin Exp Immunol. 2004 Jul;137(1):151-5. doi: 10.1111/j.1365-2249.2004.02502.x.
9
Impact of severe disease caused by respiratory syncytial virus in children living in developed countries.呼吸道合胞病毒引起的严重疾病对发达国家儿童的影响。
Pediatr Infect Dis J. 2003 Feb;22(2 Suppl):S13-8; discussion S18-20. doi: 10.1097/01.inf.0000053881.47279.d9.
10
Respiratory syncytial virus shedding by children hospitalized with lower respiratory tract infection.儿童下呼吸道感染住院时呼吸道合胞病毒的脱落。
J Med Virol. 2016 Jun;88(6):938-46. doi: 10.1002/jmv.24434. Epub 2015 Dec 1.
引用本文的文献
1
Occurrence of Central Nervous System Complications of Respiratory Syncytial Virus Infections: A Systematic Review with Meta-Analysis.呼吸道合胞病毒感染的中枢神经系统并发症的发生情况：一项系统评价与荟萃分析
Epidemiologia (Basel). 2024 Jul 19;5(3):421-455. doi: 10.3390/epidemiologia5030031.
2
Hepatic involvement in children with acute bronchiolitis.急性细支气管炎患儿的肝脏受累情况。
World J Hepatol. 2022 Oct 27;14(10):1907-1919. doi: 10.4254/wjh.v14.i10.1907.
3
Update on current views and advances on RSV infection (Review).关于 RSV 感染的最新观点和进展（综述）。
Int J Mol Med. 2020 Aug;46(2):509-520. doi: 10.3892/ijmm.2020.4641. Epub 2020 Jun 15.
4
Current practices for respiratory syncytial virus surveillance across the EU/EEA Member States, 2017.2017 年欧盟/欧洲经济区成员国的呼吸道合胞病毒监测现行做法。
Euro Surveill. 2019 Oct;24(40). doi: 10.2807/1560-7917.ES.2019.24.40.1900157.
5
Acute Encephalitis and Myocarditis Associated with Respiratory Syncytial Virus Infections.与呼吸道合胞病毒感染相关的急性脑炎和心肌炎
Turk J Anaesthesiol Reanim. 2019 Aug;47(4):348-351. doi: 10.5152/TJAR.2019.52028. Epub 2019 Mar 12.
6
Liver Dysfunction in Severe Sepsis from Respiratory Syncytial Virus.呼吸道合胞病毒所致严重脓毒症中的肝功能障碍
J Pediatr Intensive Care. 2018 Jun;7(2):110-114. doi: 10.1055/s-0037-1612609. Epub 2017 Dec 21.
本文引用的文献
1
Acute necrotizing encephalopathy: an underrecognized clinicoradiologic disorder.急性坏死性脑病：一种未被充分认识的临床放射学疾病。
Mediators Inflamm. 2015;2015:792578. doi: 10.1155/2015/792578. Epub 2015 Mar 22.
2
Respiratory syncytial virus-related encephalitis: magnetic resonance imaging findings with diffusion-weighted study.呼吸道合胞病毒相关性脑炎：磁共振成像表现及扩散加权研究
Neuroradiology. 2014 Feb;56(2):163-8. doi: 10.1007/s00234-013-1305-z. Epub 2013 Dec 13.
3
Hepatitis during respiratory syncytial virus infection--a case report.呼吸道合胞病毒感染时发生肝炎——一例报告。
Biochem Med (Zagreb). 2013;23(1):112-6. doi: 10.11613/bm.2013.014.
4
Acute necrotizing encephalopathy associated with enterovirus infection.与肠道病毒感染相关的急性坏死性脑病
Brain Dev. 2013 May;35(5):454-7. doi: 10.1016/j.braindev.2012.07.001. Epub 2012 Jul 23.
5
Epidemiology of respiratory virus infections among infants and young children admitted to hospital in Oman.阿曼住院婴儿和幼儿呼吸道病毒感染的流行病学。
J Med Virol. 2012 Aug;84(8):1323-9. doi: 10.1002/jmv.23330.
6
A case of acute necrotizing encephalopathy associated with parainfluenza virus infection.1例与副流感病毒感染相关的急性坏死性脑病
Korean J Pediatr. 2012 Apr;55(4):147-50. doi: 10.3345/kjp.2012.55.4.147. Epub 2012 Apr 30.
7
Respiratory syncytial virus infection in children.儿童呼吸道合胞病毒感染。
Am Fam Physician. 2011 Jan 15;83(2):141-6.
8
Acute necrotizing encephalopathy progressing to brain death in a pediatric patient with novel influenza A (H1N1) infection.急性坏死性脑病进展为新型甲型流感（H1N1）感染患儿脑死亡。
Clin Infect Dis. 2010 Apr 15;50(8):e50-2. doi: 10.1086/651501.
9
Acute necrotizing encephalopathy in 3 brothers.3 兄弟患急性坏死性脑病。
Pediatrics. 2010 Mar;125(3):e693-8. doi: 10.1542/peds.2009-1984. Epub 2010 Feb 8.
10
The burden of respiratory syncytial virus infection in young children.幼儿呼吸道合胞病毒感染的负担
N Engl J Med. 2009 Feb 5;360(6):588-98. doi: 10.1056/NEJMoa0804877.
Zotero 插件