Jain Anshu, Alam Kiran, Maheshwari Veena, Khan Roobina, Nobin Hage, Narula Varsha
Department of Pathology, Jawahar Lal Nehru Medical College, AMU, Aligarh, Uttar Pradesh 202002, India.
J Bone Oncol. 2013 Jul 31;2(3):132-6. doi: 10.1016/j.jbo.2013.07.003. eCollection 2013 Sep.
Primary bone lymphoma (PBL) is an uncommon clinical entity and a rare presentation of non-Hodgkin's lymphoma. PBL accounts for less than 5% of malignant bone tumors, 4-5% of extra nodal lymphoma and less than 1% of all non-Hodgkin's lymphoma. Diffuse large-B-cell lymphoma (DLBCL) accounts for the majority of cases of PBL. The incidence of PBL is so rare that many of its aspects remain unknown. A number of studies have been reported from western countries but only a few reports are available from Asia. Out of 20,000 bone lesions received in our department over 5 years, only 5 cases were primary bone lymphoma; all of which were DLBCL. We report our experience on PBLs with main emphasis on two unusual presentations of this rare tumor.
原发性骨淋巴瘤（PBL）是一种不常见的临床实体，是非霍奇金淋巴瘤的罕见表现形式。PBL占恶性骨肿瘤的比例不到5%，占结外淋巴瘤的4 - 5%，占所有非霍奇金淋巴瘤的比例不到1%。弥漫性大B细胞淋巴瘤（DLBCL）占PBL病例的大多数。PBL的发病率非常低，以至于其许多方面仍不为人知。西方国家已有多项研究报道，但亚洲仅有少数报告。在我们科室5年接收的20000例骨病变中，只有5例是原发性骨淋巴瘤；所有这些病例均为DLBCL。我们报告我们对PBL的经验，主要强调这种罕见肿瘤的两种不寻常表现。
