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Bone-targeted therapy for metastatic breast cancer-Where do we go from here? A commentary from the BONUS 8 meeting.转移性乳腺癌的骨靶向治疗——我们何去何从？来自BONUS 8会议的评论
J Bone Oncol. 2014 Feb 4;3(1):1-4. doi: 10.1016/j.jbo.2014.01.001. eCollection 2014 Mar.
2
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Are adjuvant bisphosphonates now standard of care of women with early stage breast cancer? A debate from the Canadian Bone and the Oncologist New Updates meeting.辅助双膦酸盐现在是早期乳腺癌女性的标准治疗方法吗？来自加拿大骨与肿瘤学家新进展会议的辩论。
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4
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Breast Care (Basel). 2014 Oct;9(5):323-30. doi: 10.1159/000368710.
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Bone-Targeted Agents in Breast Cancer: Do We Now Have All the Answers?乳腺癌中的骨靶向药物：我们现在有了所有答案吗？
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本文引用的文献

1
Does estrogen play a role in response to adjuvant bone-targeted therapies?雌激素在辅助性骨靶向治疗反应中起作用吗？
J Bone Oncol. 2013 Jul 5;2(4):167-73. doi: 10.1016/j.jbo.2013.06.001. eCollection 2013 Dec.
2
Effects of de-escalated bisphosphonate therapy on the Functional Assessment of Cancer Therapy-Bone Pain, Brief Pain Inventory and bone biomarkers.降阶梯双膦酸盐治疗对癌症治疗功能评估-骨痛、简明疼痛问卷和骨生物标志物的影响。
J Bone Oncol. 2013 Aug 8;2(4):154-7. doi: 10.1016/j.jbo.2013.07.004. eCollection 2013 Dec.
3
Incidence, consequences and treatment of bone metastases in breast cancer patients-Experience from a single cancer centre.乳腺癌患者骨转移的发生率、后果及治疗——来自单一癌症中心的经验
J Bone Oncol. 2013 Oct 3;2(4):137-44. doi: 10.1016/j.jbo.2013.09.001. eCollection 2013 Dec.
4
A systematic review of dosing frequency with bone-targeted agents for patients with bone metastases from breast cancer.对乳腺癌骨转移患者使用骨靶向药物给药频率的系统评价。
J Bone Oncol. 2013 May 15;2(3):123-31. doi: 10.1016/j.jbo.2013.05.001. eCollection 2013 Sep.
5
Oral care and the use of bone-targeted agents in patients with metastatic cancers: A practical guide for dental surgeons and oncologists.转移性癌症患者的口腔护理及骨靶向药物的应用：牙科医生和肿瘤学家实用指南
J Bone Oncol. 2013 Jan 1;2(1):38-46. doi: 10.1016/j.jbo.2012.12.001. eCollection 2013 Feb.
6
A national portfolio of bone oncology trials-The Canadian experience in 2012.2012年加拿大骨肿瘤试验全国项目组合情况
J Bone Oncol. 2012 Oct 17;1(3):95-100. doi: 10.1016/j.jbo.2012.09.001. eCollection 2012 Dec.
7
Histomorphometric and microarchitectural analyses using the 2 mm bone marrow trephine in metastatic breast cancer patients-preliminary results.使用2毫米骨髓环钻对转移性乳腺癌患者进行组织形态计量学和微观结构分析——初步结果
J Bone Oncol. 2012 Dec 1;1(3):69-73. doi: 10.1016/j.jbo.2012.10.003. eCollection 2012 Dec.
8
Adjuvant bisphosphonate treatment for breast cancer: Where are we heading and can the pre-clinical literature help us get there?乳腺癌的辅助双膦酸盐治疗：我们正走向何方，临床前文献能否帮助我们实现目标？
J Bone Oncol. 2012 May 24;1(1):12-7. doi: 10.1016/j.jbo.2012.04.003. eCollection 2012 Jun.
9
Myeloid-derived suppressor cells expand during breast cancer progression and promote tumor-induced bone destruction.髓源性抑制细胞在乳腺癌进展过程中扩增，并促进肿瘤诱导的骨破坏。
Oncoimmunology. 2012 Dec 1;1(9):1484-1494. doi: 10.4161/onci.21990.
10
Incidence and patterns of distant metastases for patients with early-stage breast cancer after breast conservation treatment.早期乳腺癌保乳治疗后远处转移的发生率和模式。
Clin Breast Cancer. 2013 Apr;13(2):88-94. doi: 10.1016/j.clbc.2012.11.001. Epub 2012 Dec 5.

转移性乳腺癌的骨靶向治疗——我们何去何从？来自BONUS 8会议的评论

Bone-targeted therapy for metastatic breast cancer-Where do we go from here? A commentary from the BONUS 8 meeting.

作者信息

Zhu Xiaofu, Amir Eitan, Singh Gurmit, Clemons Mark, Addison Christina

机构信息

Division of Medical Oncology, Ottawa Hospital and Faculty of Medicine, University of Ottawa, Ottawa, Canada.

Division of Medical Oncology and Hematology, University of Toronto and Princess Margaret Hospital, Toronto, Canada.

出版信息

J Bone Oncol. 2014 Feb 4;3(1):1-4. doi: 10.1016/j.jbo.2014.01.001. eCollection 2014 Mar.

DOI:10.1016/j.jbo.2014.01.001
PMID:26909291
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4723414/
Abstract

The annual Bone and The Oncologist New Updates (BONUS 8) conference focuses on the current understanding and dilemmas in the treatment and prevention of bone metastasis in cancer, as well as novel research on bone homeostasis and cancer-induced bone loss. We present commentaries from experts for their own take on where they feel the field of bone-targeted therapies for metastatic breast cancer is moving, or needs to move, if we are to make further progress.

摘要

年度骨与肿瘤学家新进展（BONUS 8）会议聚焦于当前对癌症骨转移治疗与预防的理解及困境，以及骨稳态和癌症诱导性骨丢失的新研究。我们展示了专家们对于转移性乳腺癌骨靶向治疗领域走向的见解，即如果要取得进一步进展，该领域正在或需要朝着哪个方向发展。