Cochis A, Azzimonti B, Sorrentino R, Della Valle C, De Giglio E, Bloise N, Visai L, Bruni G, Cometa S, Pezzoli D, Candiani G, Rimondini L, Chiesa R
Department of Health Sciences, Medical School, University of Piemonte Orientale (UPO), Via Solaroli 17, 28100 Novara, Italy; Department of Biomedical, Surgical and Dental Sciences, Università di Milano/ University of Milan, via Beldiletto 1, 20142 Milan, Italy.
Department of Health Sciences, Medical School, University of Piemonte Orientale (UPO), Via Solaroli 17, 28100 Novara, Italy; Consorzio Interuniversitario Nazionale per la Scienza e Tecnologia dei Materiali (INSTM), Via Giusti 9, Local Unit Piemonte Orientale, 50121 Firenze, Italy.
Data Brief. 2016 Jan 22;6:758-62. doi: 10.1016/j.dib.2016.01.024. eCollection 2016 Mar.
This paper contains original data supporting the antibacterial activities of Gallium (Ga(3+))-doped pro-osteointegrative titanium alloys, obtained via Anodic Spark Deposition (ASD), as described in "The effect of silver or gallium doped titanium against the multidrug resistant Acinetobacter baumannii" (Cochis et al. 2016) [1]. In this article we included an indirect cytocompatibility evaluation towards Saos2 human osteoblasts and extended the microbial evaluation of the Ga(3+) enriched titanium surfaces against the biofilm former Escherichia coli and Staphylococcus epidermidis strains. Cell viability was assayed by the Alamar Blue test, while bacterial viability was evaluated by the metabolic colorimetric 3-[4,5-dimethylthiazol-2-yl]-2,5 diphenyl tetrazolium bromide (MTT) assay. Finally biofilm morphology was analyzed by Scanning Electron Microscopy (SEM). Data regarding Ga(3+) activity were compared to Silver.
本文包含原始数据，支持通过阳极火花沉积（ASD）获得的镓（Ga(3+)）掺杂的促进骨整合钛合金的抗菌活性，如《银或镓掺杂钛对多重耐药鲍曼不动杆菌的影响》（科奇斯等人，2016年）[1]中所述。在本文中，我们纳入了对Saos2人成骨细胞的间接细胞相容性评估，并扩展了对富含Ga(3+)的钛表面针对生物膜形成菌大肠杆菌和表皮葡萄球菌菌株的微生物评估。通过阿拉玛蓝试验测定细胞活力，而通过代谢比色法3-[4,5-二甲基噻唑-2-基]-2,5-二苯基溴化四氮唑（MTT）试验评估细菌活力。最后，通过扫描电子显微镜（SEM）分析生物膜形态。将有关Ga(3+)活性的数据与银的数据进行了比较。
