Haakstad Lene A H, Edvardsen Elisabeth, Bø Kari
a Department of Sports Medicine , Norwegian School of Sports Sciences , Oslo , Norway.
Hypertens Pregnancy. 2016 May;35(2):170-80. doi: 10.3109/10641955.2015.1122036. Epub 2016 Feb 24.
To evaluate the effect of regular exercise on maternal arterial blood pressure (BP) at rest and during uphill walking, in healthy former inactive pregnant women.
A single-blind, single-center, randomized controlled trial including 61 out of 105 healthy, inactive nulliparous pregnant women, initially enrolled in a controlled trial studying the effect of 12 weeks of aerobic exercise (60 min 2/week) on maternal weight gain. Primary outcome was the mean adjusted difference in change in resting systolic and diastolic BP from baseline to after intervention. Secondary outcome was the mean adjusted difference in change in systolic BP during uphill treadmill walking at critical power. Measurements were performed prior to the intervention (gestation week 17.6 ± 4.2) and after the intervention (gestation week 36.5 ± 0.9).
At baseline, resting systolic and diastolic BP was 115/66 ± 12/7 and 115/67 ± 10/9 mmHg in the exercise (n = 35) and control group (n = 26), respectively. After the intervention, resting systolic BP was 112 ± 8 mmHg in the exercise group and 119 ± 14 mmHg in the control group, giving a between-group difference of 7.5 mmHg (95% CI 1.5 to 12.6, p = 0.013). Diastolic BP was 71 ± 9 and 76 ± 8 mmHg, with a between-group difference of 3.9 mmHg (95% CI -0.07 to 7.8, p = 0.054). During uphill treadmill walking at critical power, the between-group difference in systolic and diastolic BP was 5.9 mmHg (95% CI -4.4 to 16.1, p = 0.254) and 5.5 mmHg (95% CI -0.2 to 11.1, p = 0.059), respectively.
Aerobic exercise reduced resting systolic BP in healthy former inactive pregnant women.
评估规律运动对健康的既往不运动孕妇静息及上坡行走时母体动脉血压（BP）的影响。
一项单盲、单中心随机对照试验，从105名健康、不运动的初产妇中选取61名，她们最初参与了一项研究12周有氧运动（每周2次，每次60分钟）对母体体重增加影响的对照试验。主要结局是干预前后静息收缩压和舒张压变化的平均校正差异。次要结局是在临界功率下进行上坡跑步机行走时收缩压变化的平均校正差异。在干预前（妊娠第17.6±4.2周）和干预后（妊娠第36.5±0.9周）进行测量。
基线时，运动组（n = 35）和对照组（n = 26）的静息收缩压和舒张压分别为115/66±12/7和115/67±10/9 mmHg。干预后，运动组静息收缩压为112±8 mmHg，对照组为119±14 mmHg，组间差异为7.5 mmHg（95%CI 1.5至12.6，p = 0.013）。舒张压分别为71±9和76±8 mmHg，组间差异为3.9 mmHg（95%CI -0.07至7.8，p = 0.054）。在临界功率下进行上坡跑步机行走时，收缩压和舒张压的组间差异分别为5.9 mmHg（95%CI -4.4至16.1，p = 0.254）和5.5 mmHg（95%CI -0.2至11.1，p = 0.059）。
有氧运动可降低健康的既往不运动孕妇的静息收缩压。
