Baird Janis, Hill Catherine M, Harvey Nicholas C, Crozier Sarah, Robinson Sian M, Godfrey Keith M, Cooper Cyrus, Inskip Hazel
MRC Lifecourse Epidemiology Unit, University of Southampton, Southampton, UK.
Division of Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, UK.
J Sleep Res. 2016 Aug;25(4):412-8. doi: 10.1111/jsr.12389. Epub 2016 Feb 23.
Many studies have shown that shorter sleep duration in childhood is associated with higher body mass index (BMI), and have proposed that it is due to an effect of sleep on adiposity. There is little evidence about the association of sleep with fat-free mass. This study examined the association between child's sleep duration at age 3 years and fat and fat-free mass at 4 years of age in a prospective cohort study of 302 boys and 285 girls. Study participants were taking part in the Southampton Women's Survey, a longitudinal study of mothers and children from preconception onwards. Total sleep duration at age 3 years was derived from parental report of night sleep and nap duration. Body composition was assessed by Dual-energy X-ray Absorptiometry (DXA) at 4 years. Mean total sleep duration was 11.5 hours. In linear regression analyses, adjusted for potentially confounding factors (maternal educational attainment, prepregnancy BMI, smoking during pregnancy, child's gestational age at birth, age at DXA, sex, age last breastfed, dietary quality at 3 years, TV watching and hours actively on the move and parental social class), shorter sleep in hours was associated with higher BMI (kg/m(2) ) [β: -0.2340, 95% confidence interval (CI): -0.373 to -0.096], a greater fat mass index (kg) (β: -0.1182, 95% CI: -0.218 to -0.018) and a greater fat-free mass index (kg) (β: -0.100, 95% CI: -0.185 to -0.015). Previous research suggested that the association between shorter sleep and higher body mass index is due to an effect on adiposity. Our findings are novel, suggesting that the relationship between sleep and BMI is also determined by an effect on muscle.
许多研究表明，儿童期睡眠时间较短与较高的体重指数（BMI）相关，并提出这是由于睡眠对肥胖的影响。关于睡眠与去脂体重之间的关联，证据很少。在一项对302名男孩和285名女孩的前瞻性队列研究中，本研究调查了3岁儿童的睡眠时间与4岁时的脂肪及去脂体重之间的关联。研究参与者参与了南安普敦妇女调查，这是一项从孕前开始对母亲和孩子进行的纵向研究。3岁时的总睡眠时间来自父母对夜间睡眠和午睡时间的报告。4岁时通过双能X线吸收法（DXA）评估身体成分。平均总睡眠时间为11.5小时。在线性回归分析中，对潜在混杂因素（母亲教育程度、孕前BMI、孕期吸烟、孩子出生时的孕周、DXA检查时的年龄、性别、最后一次母乳喂养的年龄、3岁时的饮食质量、看电视时间、活跃运动时间以及父母社会阶层）进行校正后，睡眠时间越短与较高的BMI（kg/m²）相关[β：-0.2340，95%置信区间（CI）：-0.373至-0.096]、较高的脂肪量指数（kg）（β：-0.1182，9%CI：-0.218至-0.018）以及较高的去脂体重指数（kg）（β：-0.100，95%CI：-0.185至-0.015）。先前的研究表明，较短睡眠与较高体重指数之间的关联是由于对肥胖的影响。我们的研究结果很新颖，表明睡眠与BMI之间的关系也由对肌肉的影响所决定。
