[（15）O] H2O正电子发射断层扫描与功能磁共振成像在激活研究中的比较
Comparison of [(15)O] H2O Positron Emission Tomography and Functional Magnetic Resonance Imaging in Activation Studies.
作者信息
Kameyama Masashi, Murakami Koji, Jinzaki Masahiro
机构信息
Division of Nuclear Medicine, National Center for Global Health and Medicine, Tokyo, Japan; Division of Nuclear Medicine, Keio University, Tokyo, Japan.
Division of Nuclear Medicine, Keio University, Tokyo, Japan.
出版信息
World J Nucl Med. 2016 Jan-Apr;15(1):3-6. doi: 10.4103/1450-1147.172139.
[(15)O] H2O positron emission tomography (PET) has long been out of use in activation studies on the brain. Indeed, it is true that blood oxygen level dependent (BOLD) functional magnetic resonance imaging (fMRI) has better spatial resolution and temporal resolution than PET, as well as no radiation exposure. However, PET and fMRI differ in their scope. Compared to fMRI, [(15)O] H2O PET offers advantages such as being quantifiable, less deteriorated by movement, and allowing for longitudinal studies. This article aimed to reassess the merits of PET in this context.
[15O]水正电子发射断层扫描（PET）在大脑激活研究中早已不再使用。确实，血氧水平依赖（BOLD）功能磁共振成像（fMRI）在空间分辨率和时间分辨率方面比PET更好，而且没有辐射暴露。然而，PET和fMRI的应用范围有所不同。与fMRI相比，[15O]水PET具有可量化、受运动影响较小以及可进行纵向研究等优势。本文旨在重新评估在这种情况下PET的优点。
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