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结构明确的 Au@Cu2-xS 核壳纳米晶体用于提高基于增强光热效率的癌症治疗效果。

Structurally Well-Defined Au@Cu2- x S Core-Shell Nanocrystals for Improved Cancer Treatment Based on Enhanced Photothermal Efficiency.

机构信息

Beijing Key Laboratory of Construction Tailorable Advanced Functional Materials and Green Applications, School of Materials Science and Engineering, Beijing Institute of Technology, Beijing, 100081, P. R. China.

Institute of Applied Physics and Computational Mathematics, Beijing, 100088, P. R. China.

出版信息

Adv Mater. 2016 Apr;28(16):3094-101. doi: 10.1002/adma.201503201. Epub 2016 Feb 23.

Abstract

Au@Cu2- x S core-shell nanocrystals (NCs) have been synthesized under large lattice mismatch with high crystallinity, controllable shape, and nonstoichiometric composition. Both experimental observations and simulations are used to verify the flexible dual-mode plasmon coupling. The enhanced photothermal effect is harnessed for diverse HeLa cancer cell ablation applications in the NIR-I window (750-900 nm) and the NIR-II window (1000-1400 nm).

摘要

Au@Cu2- x S 核壳纳米晶体(NCs)在晶格失配较大的情况下合成,具有高结晶度、可控形状和非化学计量组成。实验观察和模拟都用于验证灵活的双模式等离子体耦合。在近红外-I 窗口(750-900nm)和近红外-II 窗口(1000-1400nm)中,利用增强的光热效应实现了多种 HeLa 癌细胞消融应用。

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