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卡拉胶对腹膜巨噬细胞的影响。

Influence of carrageenan on peritoneal macrophages.

作者信息

Vijayakumar R K, Palanivel V, Muthukkaruppan V R

机构信息

Department of Immunology, School of Biological Sciences, Madurai Kamaraj University, India.

出版信息

Immunol Lett. 1989 Nov;23(1):55-9. doi: 10.1016/0165-2478(89)90155-7.

Abstract

BALB/c mice were given five intraperitoneal (i.p.) injections of lambda carrageenan (CGN lambda). Following this treatment, the viability, phagocytic capacity, bactericidal activity, interleukin 1 (IL-1)-producing ability and Ia+ cell content of the peritoneal plastic-adherent macrophage population was analysed. The present study demonstrates the enhancement of bactericidal activity, inhibition of the augmented Ia+ cell content after priming with sheep red blood cells (SRBC), and impairment of IL-1 production by peritoneal macrophages, although their viability and phagocytic function remained unaltered.

摘要

给BALB/c小鼠腹腔内注射5次λ-角叉菜胶(CGNλ)。在此处理后,分析了腹腔塑料贴壁巨噬细胞群体的活力、吞噬能力、杀菌活性、产生白细胞介素1(IL-1)的能力和Ia⁺细胞含量。本研究表明,尽管腹腔巨噬细胞的活力和吞噬功能未改变,但杀菌活性增强,经绵羊红细胞(SRBC)致敏后Ia⁺细胞含量增加受到抑制,且IL-1产生受损。

相似文献

1
Influence of carrageenan on peritoneal macrophages.卡拉胶对腹膜巨噬细胞的影响。
Immunol Lett. 1989 Nov;23(1):55-9. doi: 10.1016/0165-2478(89)90155-7.

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