Vijayakumar R K, Palanivel V, Muthukkaruppan V R
Department of Immunology, School of Biological Sciences, Madurai Kamaraj University, India.
Immunol Lett. 1989 Nov;23(1):55-9. doi: 10.1016/0165-2478(89)90155-7.
BALB/c mice were given five intraperitoneal (i.p.) injections of lambda carrageenan (CGN lambda). Following this treatment, the viability, phagocytic capacity, bactericidal activity, interleukin 1 (IL-1)-producing ability and Ia+ cell content of the peritoneal plastic-adherent macrophage population was analysed. The present study demonstrates the enhancement of bactericidal activity, inhibition of the augmented Ia+ cell content after priming with sheep red blood cells (SRBC), and impairment of IL-1 production by peritoneal macrophages, although their viability and phagocytic function remained unaltered.
给BALB/c小鼠腹腔内注射5次λ-角叉菜胶（CGNλ）。在此处理后，分析了腹腔塑料贴壁巨噬细胞群体的活力、吞噬能力、杀菌活性、产生白细胞介素1（IL-1）的能力和Ia⁺细胞含量。本研究表明，尽管腹腔巨噬细胞的活力和吞噬功能未改变，但杀菌活性增强，经绵羊红细胞（SRBC）致敏后Ia⁺细胞含量增加受到抑制，且IL-1产生受损。
