Clonal Replacement Underlies Spontaneous Remission in Paroxysmal Nocturnal Haemoglobinuria.
作者信息
Babushok Daria V, Stanley Natasha, Xie Hongbo M, Huang Hugh, Bagg Adam, Olson Timothy S, Bessler Monica
机构信息
Division of Hematology, Department of Medicine, Hospital of the University of Pennsylvania, Philadelphia, PA, USA.
Comprehensive Bone Marrow Failure Center, Division of Hematology, Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, PA, USA.
出版信息
Br J Haematol. 2017 Feb;176(3):487-490. doi: 10.1111/bjh.13963. Epub 2016 Feb 23.
Abstract
摘要
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Emergence of clonal hematopoiesis in the majority of patients with acquired aplastic anemia.大多数获得性再生障碍性贫血患者出现克隆性造血。
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Deep sequencing reveals stepwise mutation acquisition in paroxysmal nocturnal hemoglobinuria.深度测序揭示阵发性夜间血红蛋白尿中逐步获得性突变。
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Paroxysmal nocturnal hemoglobinuria after autologous stem cell transplantation: extinction of the clone during treatment with eculizumab - pathophysiological implications of a unique clinical case.自体干细胞移植后阵发性睡眠性血红蛋白尿：依库珠单抗治疗期间克隆的消除——一个独特临床病例的病理生理学意义。
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Acute leukaemia in paroxysmal nocturnal haemoglobinuria. Case report and review of the literature.阵发性夜间血红蛋白尿中的急性白血病。病例报告及文献综述。
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N Engl J Med. 1995 Nov 9;333(19):1253-8. doi: 10.1056/NEJM199511093331904.
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Prolonged survival in paroxysmal nocturnal hemoglobinuria.阵发性夜间血红蛋白尿的长期存活
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