He Bo, Lu Zhibing, He Wenbo, Huang Bing, Jiang Hong
Department of Cardiology, Renmin Hospital of Wuhan University, Wuhan, China.
Cardiovascular Research Institute of Wuhan University, Wuhan, China.
Cardiovasc Ther. 2016 Jun;34(3):167-71. doi: 10.1111/1755-5922.12179.
The cardiac autonomic nervous system has been known to play an important role in the development and progression of cardiovascular diseases. Autonomic modulation by electrical stimulation of the parasympathetic nervous system, which increases the parasympathetic activity and suppresses the sympathetic activity, is emerging as a therapeutic strategy for the treatment of cardiovascular diseases. Here, we review the recent literature on autonomic modulation by electrical stimulation of the parasympathetic nervous system, including vagus nerve stimulation, transcutaneous auricular vagal stimulation, spinal cord stimulation, and ganglionated plexi stimulation, in the treatment of heart failure, atrial fibrillation, and ventricular arrhythmias.
心脏自主神经系统在心血管疾病的发生和发展中发挥着重要作用，这一点已为人所知。通过电刺激副交感神经系统来进行自主调节，可增加副交感神经活动并抑制交感神经活动，正逐渐成为治疗心血管疾病的一种策略。在此，我们综述了近期有关通过电刺激副交感神经系统进行自主调节的文献，包括迷走神经刺激、经皮耳迷走神经刺激、脊髓刺激和神经节丛刺激，用于治疗心力衰竭、心房颤动和室性心律失常。
