Guadagno Elia, De Rosa Gaetano, Del Basso De Caro Marialaura
Department of Advanced Biomedical Sciences, University of Naples Federico II, Naples, Italy.
J Clin Pathol. 2016 Jul;69(7):563-74. doi: 10.1136/jclinpath-2015-203551. Epub 2016 Feb 25.
The diagnosis of neuroendocrine tumours in typical sites, as gastrointestinal tract and lung, is based upon well-coded criteria that have become familiar to most of the pathologists. Much more difficult is the recognition and allocation of proper nomenclature to be referred to the same histotype in locations where these tumours have a lower incidence. The aim of our review was to provide a quick handbook of the main diagnostic pitfalls known in literature that can interpose in the histopathological examination of neuroendocrine tumours in rare sites (urinary system and male genital organs, female genital organs, head and neck and breast).
在典型部位(如胃肠道和肺部)的神经内分泌肿瘤诊断,基于大多数病理学家熟知的明确编码标准。而在这些肿瘤发病率较低的部位,识别并为同一组织学类型赋予恰当的命名则困难得多。我们综述的目的是提供一份快速手册,介绍文献中已知的主要诊断陷阱,这些陷阱可能出现在罕见部位(泌尿系统、男性生殖器官、女性生殖器官、头颈部和乳腺)神经内分泌肿瘤的组织病理学检查中。