1The Department of Psychology,University of Oslo,Oslo,Norway.
3The Centre for Emotions and Health,Dalhousie University,Halifax, NS,Canada.
Acta Neuropsychiatr. 2016 Oct;28(5):257-71. doi: 10.1017/neu.2016.5. Epub 2016 Feb 26.
The study investigated the effectiveness of an 8-week intensive residential treatment programme based on principles from intensive short-term dynamic psychotherapy for patients with known treatment-resistant anxiety- and/or depressive disorders (mainly with comorbid personality disorders).
Patients (N=95) with prior repeated treatment failure were included. Changes in self-reported target complaints, symptom severity, and overall interpersonal problems have been presented for these patients in two previous articles. We now expand upon the existing knowledge by presenting novel data from a number of important observer-based and self-reported outcome domains (diagnostic changes on Axis I and II, changes in overall personality dysfunction, disorder complexity, medication use, health care utilisation, and occupational activity).
There were pervasive and significant improvements on all measures during treatment, which were maintained or further improved during follow-up. Fourteen months after the end of treatment, 46.26% of patients had recovered in terms of Axis I pathology, 63.79% had recovered in terms of Axis II pathology, 71.18% had returned to work, and there was a 28.62% reduction in regular use of psychotropic medications. Health care utilisation was reduced by 65.55%, and there were large improvements in disorder complexity and levels of personality dysfunction.
The treatment programme was highly effective for patients with common and complex treatment-resistant mental disorders. Results are encouraging for the relatively large number of patients who tend not to benefit from standard formats of treatment for debilitating psychological problems.
本研究调查了基于密集短期动态心理治疗原则的 8 周强化住院治疗方案对已知治疗抵抗性焦虑和/或抑郁障碍患者(主要伴有共病人格障碍)的疗效。
纳入了先前多次治疗失败的患者(N=95)。这些患者的自我报告目标投诉、症状严重程度和整体人际问题变化已在前两篇文章中呈现。我们现在通过呈现一些重要的观察者和自我报告结果领域(轴 I 和 II 上的诊断变化、整体人格功能障碍、障碍复杂性、药物使用、医疗保健利用和职业活动的变化)的新数据来扩展现有知识。
在治疗期间,所有测量指标都有明显且广泛的改善,并且在随访期间得到维持或进一步改善。在治疗结束后 14 个月,46.26%的患者在轴 I 病理方面得到缓解,63.79%的患者在轴 II 病理方面得到缓解,71.18%的患者恢复工作,常规使用精神药物的比例下降了 28.62%。医疗保健利用减少了 65.55%,障碍复杂性和人格功能障碍水平有了很大的改善。
该治疗方案对常见且复杂的治疗抵抗性精神障碍患者非常有效。对于那些倾向于不从标准格式的治疗中受益的大量患者来说,结果令人鼓舞。