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美国老年参与者中大腿长度与代谢综合征的关系——来自 NHANES（2009-2010）的结果。

Association between upper leg length and metabolic syndrome among US elderly participants-results from the NHANES (2009-2010).

机构信息

Department of Health Science, Brock University, 500 Glenridge Ave., St. Catharines, Ontario, Canada.

出版信息

J Geriatr Cardiol. 2016 Jan;13(1):58-63. doi: 10.11909/j.issn.1671-5411.2016.01.017.

DOI:10.11909/j.issn.1671-5411.2016.01.017
PMID:26918014
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4753013/
Abstract

OBJECTIVE

To examine the relationship between upper leg length (ULL) and metabolic syndrome (MetS) in older adults.

METHODS

Data was collected from National Health and Nutritional Examination Survey (NHANES, 2009-2010). 786 individuals (385 males and 401 females) who were 60 years of age or older were included in this analysis. MetS was defined as having at least three of following conditions, i.e., central obesity, dyslipidemia, insulin resistance, and hypertension based on National Cholesterol Education Program guidelines. ULL was grouped into gender-specific tertiles.

RESULTS

328 (41.7%) of participants were categorized as having MetS (38.7% in men and 49.1% in women, P = 0.002). Compared to individuals in the 1(st) tertile (T1) of ULL, those in the 3(rd) tertile (T3) had lower levels of triglycerides (120.8 vs. 153.1 mg/dL, P = 0.045), waist circumference (100.7 vs. 104.2 cm, P = 0.049), and systolic blood pressure (126.7 vs. 131.4 mmHg, P = 0.005), but higher levels of high-density-lipoprotein cholesterol (58.1 vs. 52.4 mg/dL, P = 0.024). The odds ratios (95% CI) of MetS from multivariate logistic regression were 0.57 (0.32-1.03) for individuals in the T2 of ULL and 0.39 (0.24-0.64) for individuals in the T3 of ULL, respectively (P-value for the trend 0.022).

CONCLUSIONS

ULL was negatively associated with MetS in older adults. Further research is needed to identify potential mechanisms.

摘要

目的

探讨老年人大腿长度（ULL）与代谢综合征（MetS）的关系。

方法

数据来自国家健康与营养调查（NHANES，2009-2010 年）。本分析纳入了 786 名 60 岁或以上的个体（385 名男性和 401 名女性）。MetS 定义为根据国家胆固醇教育计划指南，至少有以下三种情况，即中心性肥胖、血脂异常、胰岛素抵抗和高血压。ULL 分为性别特异性三分位组。

结果

328 名（41.7%）参与者被归类为患有 MetS（男性 38.7%，女性 49.1%，P=0.002）。与 ULL 第 1 三分位（T1）的个体相比，ULL 第 3 三分位（T3）的个体甘油三酯水平较低（120.8 与 153.1 mg/dL，P=0.045），腰围较小（100.7 与 104.2 cm，P=0.049），收缩压较低（126.7 与 131.4 mmHg，P=0.005），但高密度脂蛋白胆固醇水平较高（58.1 与 52.4 mg/dL，P=0.024）。多元逻辑回归分析中，ULL 第 2 三分位的个体发生 MetS 的比值比（95%可信区间）为 0.57（0.32-1.03），ULL 第 3 三分位的个体为 0.39（0.24-0.64）（趋势检验 P 值=0.022）。

结论

ULL 与老年人 MetS 呈负相关。需要进一步研究以确定潜在的机制。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/93d9/4753013/59a701ed28c5/jgc-13-01-058-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/93d9/4753013/a65eda6f301a/jgc-13-01-058-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/93d9/4753013/3ab987db95c8/jgc-13-01-058-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/93d9/4753013/374fd500113a/jgc-13-01-058-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/93d9/4753013/59a701ed28c5/jgc-13-01-058-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/93d9/4753013/a65eda6f301a/jgc-13-01-058-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/93d9/4753013/3ab987db95c8/jgc-13-01-058-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/93d9/4753013/374fd500113a/jgc-13-01-058-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/93d9/4753013/59a701ed28c5/jgc-13-01-058-g004.jpg

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