Barnett Marie, McDonnell Glynnis, DeRosa Antonio, Schuler Tammy, Philip Errol, Peterson Lisa, Touza Kaitlin, Jhanwar Sabrina, Atkinson Thomas M, Ford Jennifer S
Columbia University Medical Center, New York, NY, USA.
Department of Psychiatry & Behavioral Sciences, Memorial Sloan Kettering Cancer Center, 641 Lexington Ave., 7th Floor, New York, NY, 10022, USA.
J Cancer Surviv. 2016 Oct;10(5):814-31. doi: 10.1007/s11764-016-0527-6. Epub 2016 Feb 26.
A cancer diagnosis during adolescence or young adulthood (AYA; defined as ages 15-39) generates unique medical and psychosocial needs as developmental milestones are simultaneously impacted. Past research highlights that AYAs' experiences and psychosocial outcomes are different, and more research and attention is needed. We aimed to identify and synthesize literature regarding psychosocial outcomes, unique needs, and existing psychosocial interventions pertaining to individuals diagnosed with cancer exclusively during AYA, and to highlight areas for future research.
A systematic literature search was conducted using MEDLINE (via PubMed), EMBASE, Cochrane, Web of Science, and PsycINFO (via OVID). Grey literature was searched using key term variations and combinations. Overall, 15,301 records were assessed by two independent reviewers, with 38 studies meeting inclusion criteria.
Data synthesis of the 38 articles was organized by four main themes based on quality of life and survivorship: physical well-being (7 studies), psychological well-being (8 studies), social well-being (9 studies), and survivorship care (14 studies). The paucity of studies for such broad inclusion criteria highlights that this population is often combined or subsumed under other age groups, missing needs unique to these AYAs.
AYA cancer survivors' experiences are nuanced, with interacting variables contributing to post-treatment outcomes. AYAs require age-appropriate and flexible care, informational needs and treatment-related education that foster autonomy for long-term survivorship, as well as improved follow-up care and psychological outcomes.
By incorporating these findings into practice, the informational and unmet needs of AYAs can be addressed effectively. Education and programming is lacking specific and general subject matter specific to AYAs, incorporating ranging needs at different treatment stages.
在青春期或青年期（15 - 39岁）被诊断出患有癌症会产生独特的医疗和心理社会需求，因为发育里程碑会同时受到影响。过去的研究表明，青少年和青年癌症患者的经历及心理社会结果有所不同，需要更多的研究和关注。我们旨在识别和综合有关仅在青春期或青年期被诊断为癌症的个体的心理社会结果、独特需求和现有的心理社会干预措施的文献，并突出未来研究的领域。
使用MEDLINE（通过PubMed）、EMBASE、Cochrane、科学引文索引和PsycINFO（通过OVID）进行系统的文献检索。使用关键词变体和组合搜索灰色文献。总体而言，两名独立评审员评估了15301条记录，其中38项研究符合纳入标准。
根据生活质量和生存情况，将38篇文章的数据综合分为四个主要主题：身体健康（7项研究）、心理健康（8项研究）、社会福祉（9项研究）和生存护理（14项研究）。对于如此宽泛的纳入标准，研究数量稀少，这凸显出该人群通常被合并或归入其他年龄组，从而忽略了这些青少年和青年癌症患者特有的需求。
青少年和青年癌症幸存者的经历细微复杂，相互作用的变量会影响治疗后的结果。青少年和青年癌症患者需要适合其年龄且灵活的护理、满足信息需求以及与治疗相关的教育，以促进长期生存的自主性，同时还需要改善后续护理和心理结果。
将这些研究结果应用于实践，可以有效满足青少年和青年癌症患者的信息需求以及未得到满足的需求。针对青少年和青年癌症患者的教育和规划缺乏特定和一般的主题内容，未能涵盖不同治疗阶段的各种需求。
