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斋月期间及斋月前血液透析患者的临床和生化参数

Clinical and Biochemical Parameters of Hemodialysis Patients Before and During Islamic Month of Ramadan.

作者信息

Imtiaz Salman, Salman Beena, Dhrolia Murtaza Fakhruddin, Nasir Kiran, Abbas Hasan Nasir, Ahmad Aasim

机构信息

Department of Nephrology, Dorab Patel Post Graduate Training and Research Center, The Kidney Center Post Graduate Training Institute, Karachi, Pakistan.

出版信息

Iran J Kidney Dis. 2016 Mar;10(2):75-8.

Abstract

INTRODUCTION

Month of Ramadan bring many changes in life style, especially the diet of Muslims all over the world among both fasting and nonfasting individuals. Hemodialysis patients are kept on restricted diet because of fluid and electrolytes imbalance. The aim of this study was to compare changes in the clinical and biochemical parameters in fasting and nonfasting hemodialysis patients during the Ramadan.

MATERIALS AND METHODS

In a longitudinal study, we recruited 282 patients who were on maintenance dialysis for more than 3 months. Measurements included body weight, blood pressure, serum potassium, serum albumin, and serum phosphorus at the beginning and during the last week of Ramadan.

RESULTS

There were 252 patients who were not fasted while 34 patients were those who fasted during the Ramadan. In the nonfasting hemodialysis patients, serum albumin significantly increased at the end of Ramadan (P < .001), while serum phosphorus levels (P = .004) and diastolic blood pressure (P = .002) showed a decrease as compared with the measurements before Ramadan. In the fasting group, only serum albumin had a significant increase (P < .001) during Ramadan, while other parameters were not significantly different between the two measurements.

CONCLUSIONS

Changes in dietary pattern and content during the Ramadan is safe in terms of electrolyte balance and blood pressure changes for patients on hemodialysis. It is also safe for those patients who want to fast during this month.

摘要

引言

斋月期间生活方式会发生诸多变化,尤其是全球穆斯林在禁食和非禁食人群中的饮食。由于液体和电解质失衡,血液透析患者需遵循限制饮食。本研究旨在比较斋月期间禁食和非禁食血液透析患者临床及生化参数的变化。

材料与方法

在一项纵向研究中,我们招募了282名接受维持性透析超过3个月的患者。测量指标包括斋月开始时和最后一周的体重、血压、血清钾、血清白蛋白和血清磷。

结果

252名患者未禁食,34名患者在斋月期间禁食。在非禁食血液透析患者中,斋月结束时血清白蛋白显著升高(P <.001),而血清磷水平(P =.004)和舒张压(P =.002)与斋月前测量值相比有所下降。在禁食组中,斋月期间只有血清白蛋白显著升高(P <.001),而其他参数在两次测量之间无显著差异。

结论

就血液透析患者的电解质平衡和血压变化而言,斋月期间饮食模式和内容的变化是安全的。对于本月想要禁食的患者来说也是安全的。

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