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免疫酶法检测前列腺酸性磷酸酶的临床应用

[Clinical application of immunoenzyme assay for prostatic acid phosphatase].

作者信息

Yoshida K, Sato S, Nishimura T, Akimoto M

机构信息

Department of Urology, Nippon Medical School.

出版信息

Hinyokika Kiyo. 1989 Oct;35(10):1819-22.

PMID:2692448
Abstract

We compared the values obtained by double-antibody radioimmunoassay (RIA) and immunoenzyme assay (IEA) for measuring the prostatic acid phosphatase (PAP) in human serum. Mean PAP value of IEA in normal persons was 0.582 +/- 0.228 ng/ml (M+2SD, 1.038 ng/ml). Correction of two methods in benign prostatic hypertrophy (BPH) and prostate cancer patients was excellent [r = 0.9504, Y (IEA) = -0.4378 + 0.6529X (RIA)]. False positive cases were two by IEA and one by RIA in BPH patients.

摘要

我们比较了采用双抗体放射免疫测定法(RIA)和免疫酶测定法(IEA)测定人血清中前列腺酸性磷酸酶(PAP)所获得的值。正常人IEA法测定的PAP均值为0.582±0.228 ng/ml(M + 2SD,1.038 ng/ml)。在良性前列腺增生(BPH)和前列腺癌患者中,两种方法的校正效果良好[r = 0.9504,Y(IEA)= -0.4378 + 0.6529X(RIA)]。BPH患者中,IEA法有2例假阳性病例,RIA法有1例假阳性病例。

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