Gaca A, Panitz N
Helv Chir Acta. 1981 Aug;48(3-4):465-6.
Better diagnosis of prostatic cancer by RIA of serum prostatic acid phosphatase? The results of serum determination of RIA prostatic acid phosphatase (PAP) and enzymatic serum phosphatase were compared in 267 patients with the clinical diagnosis to reveal the diagnostic value of the RIA-PAP in prostatic carcinomata. In 33 of the investigated patients (12.4%) we found elevated values of the PAP over the normal range of 0--5 ng/ml. In these 33 patients with pathologic PAP-values those with adenomata and in adenomata intracapsulated prostatic cancers had normal serum values measured enzymatically. There was no correlation between PAP-RIA results and the stage of the prostatic carcinoma. In nearly 20% we found better information by RIA-PAP than enzymatic laboratory tests, but combined with a digital investigation.
通过血清前列腺酸性磷酸酶放射免疫分析（RIA）能更好地诊断前列腺癌吗？对267例临床诊断患者的血清前列腺酸性磷酸酶（PAP）放射免疫分析测定结果与血清酶促磷酸酶进行了比较，以揭示RIA - PAP在前列腺癌中的诊断价值。在33例受调查患者（12.4%）中，我们发现PAP值高于0 - 5 ng/ml的正常范围。在这33例PAP值异常的患者中，患有腺瘤以及腺瘤内包膜前列腺癌的患者酶促测定的血清值正常。PAP - RIA结果与前列腺癌分期之间没有相关性。在近20%的患者中，我们发现RIA - PAP结合直肠指检比酶促实验室检测能提供更好的诊断信息。
