Gupta Shaan, Allen-Vercoe Emma, Petrof Elaine O
Department of Medicine, Gastrointestinal Diseases Research Unit, Queen's University, Kingston, ON, Canada.
Department of Molecular and Cellular Biology, University of Guelph, Guelph, ON, Canada.
Therap Adv Gastroenterol. 2016 Mar;9(2):229-39. doi: 10.1177/1756283X15607414.
There has been increasing interest in understanding the role of the human gut microbiome to elucidate the therapeutic potential of its manipulation. Fecal microbiota transplantation (FMT) is the administration of a solution of fecal matter from a donor into the intestinal tract of a recipient in order to directly change the recipient's gut microbial composition and confer a health benefit. FMT has been used to successfully treat recurrent Clostridium difficile infection. There are preliminary indications to suggest that it may also carry therapeutic potential for other conditions such as inflammatory bowel disease, obesity, metabolic syndrome, and functional gastrointestinal disorders.
人们对于了解人类肠道微生物群的作用以阐明其调控的治疗潜力的兴趣与日俱增。粪便微生物群移植（FMT）是将来自供体的粪便物质溶液输注到受体的肠道中，以便直接改变受体的肠道微生物组成并带来健康益处。FMT已被用于成功治疗复发性艰难梭菌感染。有初步迹象表明，它可能对其他病症如炎症性肠病、肥胖症、代谢综合征和功能性胃肠疾病也具有治疗潜力。
