Hong Daqing, Ruan Yizhe, Pu Lei, Zhong Xiang, Zhang Yuan, Zhang Yue, Deng Fei, Yang Hongling, Li Guisen, Wang Li
Division of Nephrology, Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital, Chengdu, China.
Department of Nephrology, 452nd Hospital of Chinese People's Liberation Army, Chengdu, China.
Hemodial Int. 2016 Jul;20(3):399-406. doi: 10.1111/hdi.12399. Epub 2016 Mar 1.
Introduction Lateral abdominal radiograph is suggested as an alternative to coronary artery computed tomography (CT) in evaluating vascular calcification. Simple scoring systems including pelvic radiograph scoring and abdominal scoring system were utilized to study their correlation with coronary artery calcification. Methods In 106 MHD patients, coronary artery CT, lateral abdominal, and pelvic radiograph were taken. The Agatston scoring system was applied to evaluate the degree of coronary artery calcification which was categorized according to Agatston coronary artery calcification score (CACS) ≥ 30, ≥100, ≥400, and ≥1000. Abdominal aortic calcification was scored by 4-scored and 24-scored systems. Pelvic artery calcification was scored by a 4-scored system. Sensitivities and specificities of abdominal aortic calcification scores and pelvic artery calcification scores to predict different categories of coronary artery calcification were analyzed. We studied the diagnostic capability of abdominal aorta calcification and pelvic artery calcification to predict different CACS categories by calculating likelihood ratios. Receiver operator characteristic curves were used to determine the area under the curve for each of these testing procedures. Findings The prevalence was 48(45.3%), 15 (14.2%), 11 (10.4%), 11 (10.4%), and 11 (10.4%) for CACs > 0, ≥30, ≥100, ≥400, and ≥1000, respectively. The degree of CACs was positively correlated with patient age, prevalence of diabetes, abdominal aorta scores, and pelvic calcification scores. The areas under the curves for different CACS by all X-ray scoring systems were above 0.70 except pelvic 4-scored system for diagnosing CACS ≥30, without significant difference (P > 0.05). Discussion Both lateral abdominal and pelvic plain radiographs were demonstrated as acceptable alternatives to CT in evaluating vascular calcification.
在评估血管钙化方面,建议使用腹部侧位X线片替代冠状动脉计算机断层扫描(CT)。采用包括骨盆X线评分和腹部评分系统在内的简单评分系统来研究它们与冠状动脉钙化的相关性。
对106例维持性血液透析(MHD)患者进行冠状动脉CT、腹部侧位和骨盆X线检查。应用阿加斯顿评分系统评估冠状动脉钙化程度,根据阿加斯顿冠状动脉钙化评分(CACS)≥30、≥100、≥400和≥1000进行分类。腹主动脉钙化采用4分制和24分制评分。骨盆动脉钙化采用4分制评分。分析腹主动脉钙化评分和骨盆动脉钙化评分预测不同类别冠状动脉钙化的敏感性和特异性。通过计算似然比,研究腹主动脉钙化和骨盆动脉钙化预测不同CACS类别的诊断能力。使用受试者操作特征曲线确定这些检测程序中每一个的曲线下面积。
CACS>0、≥30、≥100、≥400和≥1000的患病率分别为48(45.3%)、15(14.2%)、11(10.4%)、11(10.4%)和11(10.4%)。CACS程度与患者年龄、糖尿病患病率、腹主动脉评分和骨盆钙化评分呈正相关。除用于诊断CACS≥30的骨盆4分制系统外,所有X线评分系统对不同CACS的曲线下面积均大于0.70,差异无统计学意义(P>0.05)。
在评估血管钙化方面,腹部侧位X线片和骨盆平片均可作为CT的可接受替代方法。