Townsend C M, Singh P, Thompson J C
Department of Surgery, University of Texas Medical Branch, Galveston.
Gastroenterol Clin North Am. 1989 Dec;18(4):777-91.
The trophic effect of gut hormones may have important clinical applications for treatment of gut and pancreatic cancers. We now have developed methods by which we can quantitate gut hormone receptors in normal and neoplastic gut mucosa and pancreas. Analysis of gut and pancreatic tumors for gut hormone receptors may thus allow us to select patients with these cancers who would respond to treatment with hormones, antihormones, or hormone ablation in a manner similar to current strategies that are employed successfully for treatment of patients with breast cancer.
肠道激素的营养作用可能在胃肠道和胰腺癌的治疗中具有重要的临床应用价值。我们现已开发出一些方法，通过这些方法我们能够对正常和肿瘤性肠道黏膜及胰腺中的肠道激素受体进行定量分析。因此，对胃肠道和胰腺肿瘤进行肠道激素受体分析，可能会使我们像目前成功用于治疗乳腺癌患者的策略那样，挑选出那些对激素、抗激素或激素消融治疗有反应的胃肠道和胰腺癌患者。
