Kemaloğlu Cemal Alper
Department of Plastic, Reconstructive, and Aesthetic Surgery, Faculty of Medicine, Erciyes University, Talas, Kayseri Turkey.
Springerplus. 2016 Feb 20;5:138. doi: 10.1186/s40064-016-1808-2. eCollection 2016.
Obesity and certain medical disorders make the reconstruction of skin defects challenging. Different kind of procedure can be used for these defect, besides, skin grafting is one of the most common and simplest procedure. Fat grafting and stem cells which are located in the adipose tissue have been commonly used in plastic surgery for regeneration and rejuvenation purposes. To decrease graft failure rate we performed nanofat grafting under an autologous split-thickness skin graft in our patient who had a problematic wound.
The case of a 35-year-old female patient with a traumatic skin defect on her left anterior crural region is described herein. After subsequent flap reconstruction, the result was disappointing and the defect size was widened. The defect was treated with combined grafting (nanofat grafting under an autologous split-thickness skin graft). At the 6 months follow-up assessment after combined grafting, the integrity of the skin graft was good with excellent pliability.
Combined grafting for problematic wounds seems to be a useful technique for cases requiring reconstruction. The potential existence of stem cells may be responsible for the successful result in our patient.
肥胖和某些医学病症使得皮肤缺损的重建具有挑战性。针对这些缺损可采用不同的手术方法，此外，皮肤移植是最常见且最简单的手术之一。脂肪移植以及存在于脂肪组织中的干细胞已广泛应用于整形手术，用于再生和年轻化目的。为降低移植失败率，我们对一名伤口情况复杂的患者在自体中厚皮片下进行了纳米脂肪移植。
本文描述了一名35岁女性患者，其左小腿前侧区域存在创伤性皮肤缺损。在进行后续皮瓣重建后，结果令人失望且缺损面积扩大。该缺损采用联合移植（自体中厚皮片下纳米脂肪移植）进行治疗。联合移植后6个月的随访评估显示，皮肤移植的完整性良好，柔韧性极佳。
对于复杂伤口的联合移植似乎是一种适用于需要重建病例的有用技术。干细胞的潜在存在可能是我们患者取得成功结果的原因。
