Botha-Scheepers S A, Sarembock B
S Afr Med J. 2015 Dec;105(12):1076. doi: 10.7196/samj.2015.v105i12.10220.
Patients with inflammatory rheumatic conditions have an increased risk of infection. While this could be the result of the underlying disease, it may also be caused by the use of immunosuppressive therapies, which are needed to treat these disorders. An increasing number of patients with rheumatoid arthritis or other rheumatic diseases are using biologic therapies (biologics) in addition to the synthetic disease-modifying anti-rheumatic drugs. The side-effects and complications of these relatively new agents are unknown to many specialists (outside of rheumatology) and general practitioners. This article highlights updates on the most important infections encountered in the daily management of patients with rheumatic diseases and discusses how these may be prevented.
患有炎性风湿性疾病的患者感染风险增加。虽然这可能是潜在疾病的结果，但也可能是为治疗这些疾病而使用免疫抑制疗法所致。越来越多的类风湿关节炎或其他风湿性疾病患者除了使用合成的改善病情抗风湿药物外，还在使用生物疗法（生物制剂）。许多专科医生（风湿病学以外的）和全科医生对这些相对较新药物的副作用和并发症并不了解。本文重点介绍了风湿性疾病患者日常管理中遇到的最重要感染的最新情况，并讨论了如何预防这些感染。
