Kondowe G B, Bell A L, Middleton D, Taggart A J
Ir J Med Sci. 1989 Nov;158(11):274-7. doi: 10.1007/BF02942069.
During a five month period in the summer of 1987, seven cases of reactive arthritis were seen at Musgrave Park Hospital, Belfast. Of the seven patients, five were male and two female. Their ages ranged from 13 to 44 (mean: 26 +/- 4) years. Five patients gave a preceding short history of diarrhoea which was usually mild. All patients presented with acute inflammatory oligoarthritis which predominantly affected the lower limbs. The knees were involved in 100%, the ankles in 70% with enthesopathy in 30% of cases. The diagnosis was confirmed in all cases by positive serology for Salmonella enteritidis. In three patients, stool cultures grew a particular strain of Salmonella enteritidis (phage type 4). Six patients were HLA-B27 positive. It is not possible to estimate the prevalence of reactive arthritis in this outbreak because there were different sources of infection and the total number of gastroenteritis cases was unknown. However, gut infections with Salmonella enteritidis are becoming increasingly common in this community and throughout the Western world. Over the past two years, in our area, there has been an almost thirty-fold increase in the number of recorded cases of infections due to this organism. By far the commonest source of infection appears to be poultry and egg products.
1987年夏天的五个月期间，贝尔法斯特的马斯格雷夫公园医院共收治了7例反应性关节炎患者。7名患者中，5名男性，2名女性。年龄范围为13至44岁（平均：26±4岁）。5名患者有先前短暂的腹泻病史，通常症状较轻。所有患者均表现为急性炎症性寡关节炎，主要累及下肢。膝关节受累率为100%，踝关节受累率为70%，30%的病例有肌腱端病。所有病例通过肠炎沙门氏菌血清学阳性得以确诊。3例患者的粪便培养物培养出一种特定的肠炎沙门氏菌菌株（噬菌体4型）。6例患者HLA - B27呈阳性。由于感染源不同且肠胃炎病例总数未知，因此无法估计此次疫情中反应性关节炎的患病率。然而，肠炎沙门氏菌引起的肠道感染在该社区以及整个西方世界正变得越来越普遍。在过去两年里，在我们地区，该病原体感染的记录病例数几乎增加了30倍。迄今为止，最常见的感染源似乎是家禽和蛋类产品。
