Hajian-Tilaki K, Heidari B, Hajian-Tilaki A
Dept of Biostatistics and Epidemiology, Babol University of Medical Sciences, Babol, Iran.
Dept of Internal Medicine, Ayatollah Rohani hospital, Babol University of Medical Sciences, Babol, Iran.
Diabetes Metab Syndr. 2016 Apr-Jun;10(2 Suppl 1):S37-42. doi: 10.1016/j.dsx.2016.01.018. Epub 2016 Jan 14.
The health-related quality of life (HRQoL) is a matter of concern in elderly people with chronic diseases. The objective of this study was to investigate the impact of obesity, hypertension and diabetes on HRQoL among elderly.
A population based cross sectional study was conducted with 750 representative sample of elderly people aged 60-90 years in Babol, the northern Iran. The demographic data and the measurement of blood pressure and other anthropometric measures were collected. The validated short form (SF-36) questionnaire was used to assess the HRQoL. A multiple linear regression model was applied to assess the impact of obesity, abdominal obesity, hypertension and diabetes on QoL.
The mean age (SD) of participants was 68.0±7.6 and 67.7±7.9 years for men and women respectively. Diabetes exerted the most negative effect on QoL score (adjusted coefficient=-9.2, 95% CI: -11.7, -6.5 points) followed by abdominal obesity and hypertension. Whereas a combination of three conditions was associated with a greater significant reduction in QoL scores in both sexes(adjusted coefficient=-14.5, 95% CI: -19.0, -9.9 points). However, the negative influence of obesity and hypertension on QoL was significant only in women.
Most components of the QoL is affected by diabetes, obesity and hypertension particularly in women. Diabetes alone or in combination with other conditions has a negative influence in both sexes with greater effect in women. These findings justify further professional support to compensate the negative influences chronic conditions on health-related QoL especially for older obese diabetic women.
健康相关生活质量（HRQoL）是慢性病老年人群关注的问题。本研究的目的是调查肥胖、高血压和糖尿病对老年人HRQoL的影响。
在伊朗北部巴博勒对750名年龄在60 - 90岁的具有代表性的老年人样本进行了一项基于人群的横断面研究。收集了人口统计学数据、血压测量值和其他人体测量指标。使用经过验证的简短形式（SF - 36）问卷来评估HRQoL。应用多元线性回归模型来评估肥胖、腹型肥胖、高血压和糖尿病对生活质量的影响。
参与者的平均年龄（标准差）男性为68.0±7.6岁，女性为67.7±7.9岁。糖尿病对生活质量评分的负面影响最大（调整系数 = -9.2，95%置信区间：-11.7，-6.5分），其次是腹型肥胖和高血压。而三种情况同时存在与两性生活质量评分的显著更大幅度降低相关（调整系数 = -14.5，95%置信区间：-19.0，-9.9分）。然而，肥胖和高血压对生活质量的负面影响仅在女性中显著。
生活质量的大多数组成部分受到糖尿病、肥胖和高血压的影响，尤其是在女性中。单独的糖尿病或与其他情况合并存在对两性均有负面影响，对女性的影响更大。这些发现证明需要进一步提供专业支持，以弥补慢性病对健康相关生活质量的负面影响，特别是对于老年肥胖糖尿病女性。
