Song Jeong-Yeop, Cho Youn Hee, Kim Mi A, Kim Jeong-Ae, Lee Chun Tek, Lee Moon Sung
Jeong-Yeop Song, Youn Hee Cho, Mi A Kim, Jeong-Ae Kim, Chun Tek Lee, Division of Gastroenterology, Department of Internal Medicine, LCT Hospital, Suwon 442-130, South Korea.
World J Gastroenterol. 2016 Feb 28;22(8):2621-9. doi: 10.3748/wjg.v22.i8.2621.
To evaluate the full-spectrum endoscopy (FUSE) colonoscopy system as the first report on the utility thereof in a Korean population.
We explored the efficacy of the FUSE colonoscopy in a retrospective, single-center feasibility study performed between February 1 and July 20, 2015. A total of 262 subjects (age range: 22-80) underwent the FUSE colonoscopy for colorectal cancer screening, polyp surveillance, or diagnostic evaluation. The cecal intubation success rate, the polyp detection rate (PDR), the adenoma detection rate (ADR), and the diverticulum detection rate (DDR), were calculated. Also, the success rates of therapeutic interventions were evaluated with biopsy confirmation.
All patients completed the study and the success rates of cecal and terminal ileal intubation were 100% with the FUSE colonoscope; we found 313 polyps in 142 patients and 173 adenomas in 95. The overall PDR, ADR and DDR were 54.2%, 36.3%, and 25.2%, respectively, and were higher in males, and increased with age. The endoscopists and nurses involved considered that the full-spectrum colonoscope improved navigation and orientation within the colon. No colonoscopy was aborted because of colonoscope malfunction.
The FUSE colonoscopy yielded a higher PDR, ADR, DDR than did traditional colonoscopy, without therapeutic failure or complications, showing feasible, effective, and safe in this first Korean trial.
评估全谱内镜（FUSE）结肠镜系统，这是关于其在韩国人群中应用的首份报告。
在2015年2月1日至7月20日进行的一项回顾性单中心可行性研究中，我们探究了FUSE结肠镜检查的疗效。共有262名受试者（年龄范围：22 - 80岁）接受了FUSE结肠镜检查，用于结直肠癌筛查、息肉监测或诊断评估。计算盲肠插管成功率、息肉检出率（PDR）、腺瘤检出率（ADR）和憩室检出率（DDR）。此外，通过活检确认评估治疗干预的成功率。
所有患者均完成研究，使用FUSE结肠镜时盲肠和回肠末端插管成功率均为100%；我们在142名患者中发现了313个息肉，在95名患者中发现了173个腺瘤。总体PDR、ADR和DDR分别为54.2%、36.3%和25.2%，男性的这些比率更高，且随年龄增加。参与的内镜医师和护士认为全谱结肠镜改善了结肠内的导航和定位。没有因结肠镜故障而中止结肠镜检查。
在这项韩国首次试验中，FUSE结肠镜检查的PDR、ADR、DDR高于传统结肠镜检查，且无治疗失败或并发症，显示出可行、有效且安全。
