Shalaby Michael M, Riahi Ryan R, Rosen Les B, Soine Erik J
Medical School, Louisiana State University Health Sciences Center, New Orleans, LA, USA.
Department of Dermatology, Louisiana State University, New Orleans, LA, USA.
Dermatol Pract Concept. 2016 Jan 31;6(1):9-13. doi: 10.5826/dpc.0601a04. eCollection 2016 Jan.
The neutrophilic dermatoses are a group of disorders characterized by skin lesions for which histological examination reveals intense epidermal and/or dermal inflammatory infiltrates composed primarily of neutrophils without evidence of infection. The myelodysplastic syndromes consist of a heterogeneous group of malignant hematopoietic stem cell disorders characterized by dysplastic and inadequate blood cell production with a variable risk of transformation to acute leukemia. Rarely, histiocytoid Sweet's syndrome occurring in patients with myelodysplastic syndrome has been described. We present a case of a 66-year-old woman with a history of myelodysplastic syndrome who developed histiocytoid Sweet's syndrome. We also review the literature and characterize patients with myelodysplastic syndrome who have developed histiocytoid Sweet's syndrome.
嗜中性皮肤病是一组以皮肤损害为特征的疾病，组织学检查显示表皮和/或真皮有强烈的炎症浸润，主要由中性粒细胞组成，无感染证据。骨髓增生异常综合征是一组异质性的恶性造血干细胞疾病，其特征是血细胞生成发育异常且不足，转化为急性白血病的风险各异。很少有文献描述骨髓增生异常综合征患者发生组织细胞样Sweet综合征的情况。我们报告一例66岁有骨髓增生异常综合征病史的女性发生组织细胞样Sweet综合征的病例。我们还回顾了文献并描述了发生组织细胞样Sweet综合征的骨髓增生异常综合征患者的特征。
