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米卡芬净治疗念珠菌尿症:病例系列报道

Micafungin in the treatment of candiduria: A case series.

作者信息

Kane Lauren E, Muzevich Katie M

机构信息

Department of Pharmacy, VCU Health, Richmond, VA, United States.

出版信息

Med Mycol Case Rep. 2016 Jan 30;11:5-8. doi: 10.1016/j.mmcr.2016.01.003. eCollection 2016 Mar.

Abstract

Echinocandin antifungal agents are not routinely recommended for the treatment of candiduria due to low urine concentrations and a paucity of clinical data supporting this indication. This report presents five cases describing the use of micafungin for the treatment of candiduria. Each patient received parenteral micafungin for a minimum of 6 days and had resolution of baseline fungal within 30 days of treatment completion.

摘要

由于尿液浓度低且缺乏支持该适应症的临床数据,棘白菌素类抗真菌药物通常不推荐用于治疗念珠菌尿症。本报告介绍了5例使用米卡芬净治疗念珠菌尿症的病例。每位患者接受静脉注射米卡芬净至少6天,并且在治疗完成后30天内基线真菌得到清除。

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本文引用的文献

2
Echinocandin Resistance in Candida.念珠菌中的棘白菌素耐药性
Clin Infect Dis. 2015 Dec 1;61 Suppl 6(Suppl 6):S612-7. doi: 10.1093/cid/civ791.
4
Is Fluconazole or an Echinocandin the Agent of Choice for Candidemia.氟康唑或棘白菌素是念珠菌血症的首选药物吗?
Ann Pharmacother. 2015 Sep;49(9):1068-74. doi: 10.1177/1060028015590838. Epub 2015 Jun 23.
5
Echinocandin resistance: an emerging clinical problem?棘白菌素耐药性:一个新出现的临床问题?
Curr Opin Infect Dis. 2014 Dec;27(6):484-92. doi: 10.1097/QCO.0000000000000111.
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Candida urinary tract infections--treatment.念珠菌性尿路感染——治疗。
Clin Infect Dis. 2011 May;52 Suppl 6:S457-66. doi: 10.1093/cid/cir112.
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Candida urinary tract infections--epidemiology.念珠菌性尿路感染——流行病学。
Clin Infect Dis. 2011 May;52 Suppl 6:S433-6. doi: 10.1093/cid/cir109.

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