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The Role of Echinocandins in Candida Biofilm-Related Vascular Catheter Infections: In Vitro and In Vivo Model Systems.棘白菌素类药物在念珠菌生物膜相关血管导管感染中的作用：体外和体内模型系统。
Clin Infect Dis. 2015 Dec 1;61 Suppl 6:S618-21. doi: 10.1093/cid/civ815.
2
Echinocandin Resistance in Candida.念珠菌中的棘白菌素耐药性
Clin Infect Dis. 2015 Dec 1;61 Suppl 6(Suppl 6):S612-7. doi: 10.1093/cid/civ791.
3
Candiduria in Catheter Associated Urinary Tract Infection with Special Reference to Biofilm Production.导尿管相关尿路感染中的念珠菌尿症，特别提及生物膜的产生
J Clin Diagn Res. 2015 Oct;9(10):DC11-3. doi: 10.7860/JCDR/2015/13910.6690. Epub 2015 Oct 1.
4
Is Fluconazole or an Echinocandin the Agent of Choice for Candidemia.氟康唑或棘白菌素是念珠菌血症的首选药物吗？
Ann Pharmacother. 2015 Sep;49(9):1068-74. doi: 10.1177/1060028015590838. Epub 2015 Jun 23.
5
Echinocandin resistance: an emerging clinical problem?棘白菌素耐药性：一个新出现的临床问题？
Curr Opin Infect Dis. 2014 Dec;27(6):484-92. doi: 10.1097/QCO.0000000000000111.
6
Micafungin at physiological serum concentrations shows antifungal activity against Candida albicans and Candida parapsilosis biofilms.在生理血清浓度下，米卡芬净对白色念珠菌和近平滑念珠菌生物膜具有抗真菌活性。
Antimicrob Agents Chemother. 2014 Sep;58(9):5581-4. doi: 10.1128/AAC.02738-14. Epub 2014 Jun 23.
7
A case of Candida glabrata severe urinary sepsis successfully treated with micafungin.1例光滑念珠菌所致严重尿源性脓毒症经米卡芬净成功治疗
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8
Distribution and antifungal susceptibility of Candida species causing nosocomial candiduria.引起医院获得性尿念珠菌病的念珠菌属种的分布及抗真菌药敏性。
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9
Candida urinary tract infections--treatment.念珠菌性尿路感染——治疗。
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Candida urinary tract infections--epidemiology.念珠菌性尿路感染——流行病学。
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米卡芬净治疗念珠菌尿症：病例系列报道

Micafungin in the treatment of candiduria: A case series.

作者信息

Kane Lauren E, Muzevich Katie M

机构信息

Department of Pharmacy, VCU Health, Richmond, VA, United States.

出版信息

Med Mycol Case Rep. 2016 Jan 30;11:5-8. doi: 10.1016/j.mmcr.2016.01.003. eCollection 2016 Mar.

DOI:10.1016/j.mmcr.2016.01.003
PMID:26937340
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4752815/
Abstract

Echinocandin antifungal agents are not routinely recommended for the treatment of candiduria due to low urine concentrations and a paucity of clinical data supporting this indication. This report presents five cases describing the use of micafungin for the treatment of candiduria. Each patient received parenteral micafungin for a minimum of 6 days and had resolution of baseline fungal within 30 days of treatment completion.

摘要

由于尿液浓度低且缺乏支持该适应症的临床数据，棘白菌素类抗真菌药物通常不推荐用于治疗念珠菌尿症。本报告介绍了5例使用米卡芬净治疗念珠菌尿症的病例。每位患者接受静脉注射米卡芬净至少6天，并且在治疗完成后30天内基线真菌得到清除。