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棘白菌素类药物在念珠菌生物膜相关血管导管感染中的作用：体外和体内模型系统。

The Role of Echinocandins in Candida Biofilm-Related Vascular Catheter Infections: In Vitro and In Vivo Model Systems.

机构信息

Center for Medical Mycology, Department of Dermatology, Case Western Reserve University, Cleveland, Ohio.

Infectious Diseases Unit, Third Department of Pediatrics, Faculty of Medicine, Aristotle University School of Health Sciences, Hippokration Hospital, Thessaloniki, Greece.

出版信息

Clin Infect Dis. 2015 Dec 1;61 Suppl 6:S618-21. doi: 10.1093/cid/civ815.

DOI:10.1093/cid/civ815
PMID:26567279
Abstract

Candida biofilm-associated infections of central venous catheters are a challenging therapeutic problem. Recent in vitro and in vivo studies of the structure, formation, pathogenesis, and treatment establish a rationale for new approaches to management of these tenacious infections.

摘要

中心静脉导管相关念珠菌生物膜感染是一个具有挑战性的治疗难题。最近关于其结构、形成、发病机制和治疗的体外和体内研究为这些顽强感染的新治疗方法提供了依据。

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