用辣根过氧化物酶标记的α-银环蛇毒素鉴定视网膜中的突触乙酰胆碱受体位点。
Identification of synaptic acetylcholine receptor sites in retina with peroxidase-labeled alpha-bungarotoxin.
作者信息
Vogel Z, Maloney G J, Ling A, Daniels M P
出版信息
Proc Natl Acad Sci U S A. 1977 Aug;74(8):3268-72. doi: 10.1073/pnas.74.8.3268.
Abstract
An alpha-bungarotoxin-horseradish peroxidase conjugate, which binds specificity to nicotinic acetylcholine receptors, was synthesized. This conjugate was bound by 5-7% of the synapses in the inner plexiform layer of the chicken retina. Bipolar ribbon synapses as well as amacrine synapses bound the conjugate.
摘要
合成了一种与烟碱型乙酰胆碱受体特异性结合的α-银环蛇毒素-辣根过氧化物酶偶联物。该偶联物与鸡视网膜内网状层中5%-7%的突触结合。双极带状突触以及无长突细胞突触均与该偶联物结合。
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