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一项针对未经筛选的急诊科患者群体的回顾性队列研究中生命体征与死亡率之间的关联。

The association between vital signs and mortality in a retrospective cohort study of an unselected emergency department population.

作者信息

Ljunggren Malin, Castrén Maaret, Nordberg Martin, Kurland Lisa

机构信息

Department of Clinical Science and Education, Södersjukhuset, Section of Emergency Medicine, Karolinska Institutet, Stockholm, Sweden.

Department of Emergency Medicine and Services, Helsinki University Hospital and Helsinki University, Helsinki, Finland.

出版信息

Scand J Trauma Resusc Emerg Med. 2016 Mar 3;24:21. doi: 10.1186/s13049-016-0213-8.

Abstract

BACKGROUND

Vital signs are widely used in emergency departments. Previous studies on the association between vital signs and mortality in emergency departments have been restricted to selected patient populations. We aimed to study the association of vital signs and age with 1-day mortality in patients visiting the emergency department.

METHODS

This retrospective cohort included patients visiting the emergency department for adults at Södersjukhuset, Sweden from 4/1/2012 to 4/30/2013. Exclusion criteria were: age < 18 years, deceased upon arrival, chief complaint circulatory or respiratory arrest, key data missing and patients who were directed to a certain fast track for conditions demanding little resources. Vital sign data was collected through the Rapid Emergency Triage and Treatment System - Adult (RETTS-A). Descriptive analyses and logistic regression models were used. The main outcome measure was 1-day mortality.

RESULTS

The 1-day mortality rate was 0.3%. 96,512 patients met the study criteria. After adjustments of differences in the other vital signs, comorbidities, gender and age the following vital signs were independently associated with 1-day mortality: oxygen saturation, systolic blood pressure, temperature, level of consciousness, respiratory rate, pulse rate and age. The highest odds ratios was observed when comparing unresponsive to alert patients (OR 31.0, CI 16.9 to 56.8), patients ≥ 80 years to <50 years (OR 35.9, CI 10.7 to 120.2) and patients with respiratory rates <8/min to 8-25/min (OR 18.1, CI 2.1 to 155.5).

DISCUSSION

Most of the vital signs used in the ED are significantly associated with one-day mortality. The more the vital signs deviate from the normal range, the larger are the odds of mortality. We did not find a suitable way to adjust for the inherent influence the triage system and medical treatment has had on mortality.

CONCLUSIONS

Most deviations of vital signs are associated with 1-day mortality. The same triage level is not associated with the same odds for death with respect to the individual vital sign. Patients that were unresponsive or had low respiratory rates or old age had the highest odds of 1-day mortality.

摘要

背景

生命体征在急诊科广泛应用。以往关于急诊科生命体征与死亡率之间关联的研究局限于特定患者群体。我们旨在研究急诊科就诊患者的生命体征及年龄与1日死亡率之间的关联。

方法

这项回顾性队列研究纳入了2012年1月4日至2013年4月30日期间在瑞典南泰利耶医院急诊科就诊的成年患者。排除标准为:年龄<18岁、到达时已死亡、主诉循环或呼吸骤停、关键数据缺失以及因病情所需资源少而被分流至特定快速通道的患者。生命体征数据通过成人快速急诊分诊与治疗系统(RETTS-A)收集。采用描述性分析和逻辑回归模型。主要结局指标为1日死亡率。

结果

1日死亡率为0.3%。96512例患者符合研究标准。在对其他生命体征、合并症、性别和年龄差异进行调整后,以下生命体征与1日死亡率独立相关:血氧饱和度、收缩压、体温、意识水平、呼吸频率、脉搏率和年龄。在比较无反应患者与警觉患者时(比值比31.0,95%置信区间16.9至56.8)、≥80岁患者与<50岁患者时(比值比35.9,95%置信区间10.7至120.2)以及呼吸频率<8次/分钟患者与8 - 25次/分钟患者时(比值比18.1,95%置信区间2.1至155.5)观察到最高的比值比。

讨论

急诊科使用的大多数生命体征与1日死亡率显著相关。生命体征偏离正常范围越明显,死亡几率越大。我们未找到合适的方法来调整分诊系统和医疗治疗对死亡率的内在影响。

结论

大多数生命体征偏差与1日死亡率相关。就个体生命体征而言,相同的分诊级别与相同的死亡几率无关。无反应或呼吸频率低或年龄大的患者1日死亡率几率最高。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/92b4/4778316/158bc1c657b3/13049_2016_213_Fig1_HTML.jpg

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