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通过卷积神经网络进行药物-药物相互作用提取

Drug-Drug Interaction Extraction via Convolutional Neural Networks.

作者信息

Liu Shengyu, Tang Buzhou, Chen Qingcai, Wang Xiaolong

机构信息

Key Laboratory of Network Oriented Intelligent Computation, Harbin Institute of Technology Shenzhen Graduate School, Shenzhen 518055, China.

出版信息

Comput Math Methods Med. 2016;2016:6918381. doi: 10.1155/2016/6918381. Epub 2016 Jan 31.

Abstract

Drug-drug interaction (DDI) extraction as a typical relation extraction task in natural language processing (NLP) has always attracted great attention. Most state-of-the-art DDI extraction systems are based on support vector machines (SVM) with a large number of manually defined features. Recently, convolutional neural networks (CNN), a robust machine learning method which almost does not need manually defined features, has exhibited great potential for many NLP tasks. It is worth employing CNN for DDI extraction, which has never been investigated. We proposed a CNN-based method for DDI extraction. Experiments conducted on the 2013 DDIExtraction challenge corpus demonstrate that CNN is a good choice for DDI extraction. The CNN-based DDI extraction method achieves an F-score of 69.75%, which outperforms the existing best performing method by 2.75%.

摘要

药物-药物相互作用(DDI)提取作为自然语言处理(NLP)中一项典型的关系提取任务,一直备受关注。大多数最先进的DDI提取系统基于支持向量机(SVM),带有大量手动定义的特征。最近,卷积神经网络(CNN)作为一种几乎不需要手动定义特征的强大机器学习方法,在许多NLP任务中展现出了巨大潜力。值得将CNN用于DDI提取,而这一点此前从未被研究过。我们提出了一种基于CNN的DDI提取方法。在2013年DDIExtraction挑战语料库上进行的实验表明,CNN是DDI提取的一个不错选择。基于CNN的DDI提取方法获得了69.75%的F值,比现有的最佳性能方法高出2.75%。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3ca7/4752975/729470b2aafa/CMMM2016-6918381.001.jpg

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