Anti-hemojuvelin antibody corrects anemia caused by inappropriately high hepcidin levels.
作者信息
Kovac Suzana, Böser Preethne, Cui Yifang, Ferring-Appel Dunja, Casarrubea Daniela, Huang Lili, Fung Emma, Popp Andreas, Mueller Bernhard K, Hentze Matthias W
机构信息
European Molecular Biology Laboratory (EMBL), Heidelberg, Germany.
Abbvie Deutschland GmbH & Co KG, Ludwigshafen, Germany.
出版信息
Haematologica. 2016 May;101(5):e173-6. doi: 10.3324/haematol.2015.140772. Epub 2016 Mar 4.
Abstract
摘要
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本文引用的文献
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Anti-repulsive Guidance Molecule C (RGMc) Antibodies Increases Serum Iron in Rats and Cynomolgus Monkeys by Hepcidin Downregulation.抗排斥导向分子C（RGMc）抗体通过下调铁调素增加大鼠和食蟹猴的血清铁水平。
AAPS J. 2015 Jul;17(4):930-8. doi: 10.1208/s12248-015-9770-4. Epub 2015 Apr 22.
2
A fully human anti-hepcidin antibody modulates iron metabolism in both mice and nonhuman primates.一种全人源抗肝素肽抗体可调节小鼠和非人灵长类动物的铁代谢。
Blood. 2013 Oct 24;122(17):3054-61. doi: 10.1182/blood-2013-06-505792. Epub 2013 Aug 14.
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Biochim Biophys Acta. 2012 Sep;1823(9):1434-43. doi: 10.1016/j.bbamcr.2012.01.014. Epub 2012 Jan 26.
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Blood. 2010 Nov 18;116(20):4045-59. doi: 10.1182/blood-2010-08-300541. Epub 2010 Oct 25.
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