Liu F, Bian D, Zheng H Q, Cheng R F
Zhongguo Yao Li Xue Bao. 1989 Sep;10(5):457-60.
The effects of aminophylline (Ami) on immune systems in normal NIH mice were studied. Ami ig 25, 50 and 100 mg/(kg.d) x 8-10 d increased hemolytic ability of plaque forming cells and antibody concentration while it decreased the delayed type hypersensitivity (DTH) reaction and peripheral white blood cells phagocytosing function. Ami 1, 5, 10 micrograms/ml also promoted lymphocyte transformation of [methyl-3H] TdR incorporation induced by PHA in vitro.
研究了氨茶碱（Ami）对正常NIH小鼠免疫系统的影响。Ami按25、50和100mg/（kg·d）灌胃8 - 10天，可提高空斑形成细胞的溶血能力和抗体浓度，同时降低迟发型超敏反应（DTH）及外周血白细胞吞噬功能。Ami 1、5、10μg/ml在体外也可促进PHA诱导的[甲基 - 3H]胸苷掺入法检测的淋巴细胞转化。
