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深度低温循环停搏下肺动脉内膜剥脱术后的急性疼痛及镇痛需求

Acute Pain and Analgesic Requirements After Pulmonary Endarterectomy With Deep Hypothermic Circulatory Arrest.

作者信息

Giménez-Milà Marc, Videla Sebastian, Jenkins David, Klein Andrew A, Gerrard Caroline, Nalpon Jacinta, Valchanov Kamen

机构信息

Department of Anaesthesia and Intensive Care, Papworth Hospital, Cambridge, United Kingdom;.

Department of Experimental and Health Sciences, Universitat Pompeu Fabra, Barcelona, Catalonia, Spain.

出版信息

J Cardiothorac Vasc Anesth. 2016 Aug;30(4):993-6. doi: 10.1053/j.jvca.2015.11.013. Epub 2015 Nov 19.

Abstract

OBJECTIVES

To assess postoperative pain intensity and the analgesic requirements in the postoperative period in patients undergoing sternotomy for pulmonary endarterectomy involving deep hypothermic circulatory arrest.

DESIGN

Retrospective cohort study.

SETTING

Single-center hospital study.

PARTICIPANTS

Patients 18 years and older undergoing sternotomy for cardiac surgery between August 2012 and August 2014.

INTERVENTIONS

No modification to usual clinical practice.

MEASUREMENTS AND MAIN RESULTS

Intraoperative opioid and steroid administration, referral to the chronic pain unit, intensive care unit pain scores, and analgesic administration in the first 48 hours after the admission to the intensive care unit were recorded. Postoperative pain was evaluated by means of a categoric verbal scale from no pain (0) to severe pain (3); this is the routine analgesic scale used in the authors' intensive care unit. A total of 200 consecutive patients undergoing pulmonary endarterectomy (PEA group) were included in the study. No patient in the PEA group received morphine during surgery. The mean (standard deviation) postoperative pain intensity score at 24 hours was 0.30 (0.54) in the PEA group. Postoperative morphine was administered in 39% of patients. No PEA patient was referred to the chronic pain unit after hospital discharge.

CONCLUSION

The total analgesic requirements and pain score of patients undergoing sternotomy for pulmonary endarterectomy with deep hypothermic circulatory arrest seemed to be low.

摘要

目的

评估在接受涉及深低温循环骤停的肺动脉内膜剥脱术的胸骨切开术患者术后疼痛强度及术后镇痛需求。

设计

回顾性队列研究。

地点

单中心医院研究。

参与者

2012年8月至2014年8月期间接受心脏手术胸骨切开术的18岁及以上患者。

干预措施

未对常规临床实践进行修改。

测量指标及主要结果

记录术中阿片类药物和类固醇的使用情况、转至慢性疼痛科的情况、重症监护病房的疼痛评分以及入住重症监护病房后48小时内的镇痛药物使用情况。术后疼痛通过从无疼痛(0)到重度疼痛(3)的分类语言量表进行评估;这是作者所在重症监护病房使用的常规镇痛量表。共有200例连续接受肺动脉内膜剥脱术的患者(肺动脉内膜剥脱术组)纳入研究。肺动脉内膜剥脱术组无患者在手术期间接受吗啡治疗。肺动脉内膜剥脱术组术后24小时的平均(标准差)疼痛强度评分为0.30(0.54)。39%的患者术后使用了吗啡。出院后无肺动脉内膜剥脱术患者被转至慢性疼痛科。

结论

接受伴有深低温循环骤停的肺动脉内膜剥脱术的胸骨切开术患者的总镇痛需求和疼痛评分似乎较低。

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