Fan Liwen, Wang Tao, Tian Ying, Xiong Fei, Wu Simei, Liang Qingjin, Zhao Junfeng
College of Chemistry & Chemical Engineering, Jiangxi Normal University, 99, Ziyang Road, Nanchang, Jiangxi 330022, P. R. China.
Chem Commun (Camb). 2016 Apr 7;52(31):5375-8. doi: 10.1039/c6cc00946h.
A copper-catalyzed oxidative coupling between quinazoline 3-oxides and unactivated aldehydes was described. The reaction worked well for both aliphatic and aromatic aldehydes and produced not only the direct oxidative coupling ketones but also cyclic hydroxamic esters derived from quinazolines.