NEUROBIOLOGICAL EVIDENCE SUPPORTING GLUTAMATE'S ROLE IN PEDIATRIC OBSESSIVE COMPULSIVE DISORDER.
作者信息
MacMaster Frank P, Rosenberg David R
机构信息
Assistant Professor, Cuthbertson and Fischer Chair in Pediatric Mental Health, Departments of Psychiatry and Pediatrics, University of Calgary, Calgary, AB, Canada.
Professor, Miriam L. Hamburger Endowed Chair of Child Psychiatry, Department of Psychiatry & Behavioral Neurosciences, Wayne State University, Detroit, MI, USA.
出版信息
Child Adolesc Psychopharmacol News. 2010 Dec;15(6):6-10. doi: 10.1521/capn.2010.15.6.6.
Abstract
摘要
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本文引用的文献
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Glutamate system genes associated with ventral prefrontal and thalamic volume in pediatric obsessive-compulsive disorder.与儿童强迫症患者腹侧前额叶和丘脑体积相关的谷氨酸系统基因。
Brain Imaging Behav. 2009 Mar 1;3(1):64-76. doi: 10.1007/s11682-008-9050-3.
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Glutamate receptor gene (GRIN2B) associated with reduced anterior cingulate glutamatergic concentration in pediatric obsessive-compulsive disorder.谷氨酸受体基因（GRIN2B）与儿童强迫症患者前扣带回谷氨酸能浓度降低有关。
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Anterior cingulate glutamate-glutamine levels predict symptom severity in women with obsessive-compulsive disorder.前扣带回谷氨酸-谷氨酰胺水平可预测强迫症女性患者的症状严重程度。
Aust N Z J Psychiatry. 2008 Jun;42(6):467-77. doi: 10.1080/00048670802050546.
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An open-label trial of riluzole, a glutamate antagonist, in children with treatment-resistant obsessive-compulsive disorder.一项针对难治性强迫症儿童的开放性试验，使用谷氨酸拮抗剂利鲁唑。
J Child Adolesc Psychopharmacol. 2007 Dec;17(6):761-7. doi: 10.1089/cap.2007.0021.
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Association of the SLC1A1 glutamate transporter gene and obsessive-compulsive disorder.溶质载体家族1成员1（SLC1A1）谷氨酸转运体基因与强迫症的关联。
Am J Med Genet B Neuropsychiatr Genet. 2007 Dec 5;144B(8):1027-33. doi: 10.1002/ajmg.b.30533.
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Cortico-striatal synaptic defects and OCD-like behaviours in Sapap3-mutant mice.Sapap3基因敲除小鼠的皮质-纹状体突触缺陷及类强迫症行为
Nature. 2007 Aug 23;448(7156):894-900. doi: 10.1038/nature06104.
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Association study between the NMDA receptor 2B subunit gene (GRIN2B) and schizophrenia: a HuGE review and meta-analysis.N-甲基-D-天冬氨酸受体2B亚基基因（GRIN2B）与精神分裂症的关联研究：一项健康影响评估回顾与荟萃分析
Genet Med. 2007 Jan;9(1):4-8. doi: 10.1097/01.gim.0000250507.96760.4b.
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Association of the glutamate receptor subunit gene GRIN2B with attention-deficit/hyperactivity disorder.谷氨酸受体亚基基因GRIN2B与注意力缺陷多动障碍的关联。
Genes Brain Behav. 2007 Jul;6(5):444-52. doi: 10.1111/j.1601-183X.2006.00273.x. Epub 2006 Sep 8.
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