Hackel H, Burg G, Lechner W, Stolz W, Ring J, Braun-Falco O
Dermatologische Klinik und Poliklinik, Julius-Maximilians-Universität Würzburg.
Hautarzt. 1989 Dec;40(12):763-6.
Keratoacanthoma centrifugum marginatum (KCM) is a rare distinct variant of keratoacanthoma. Based on three personal observations and a review of the literature, the authors describe the clinical and histological features of this neoplasm. Clinically KCM is characterized by the lack of a tendency for spontaneous remission and by continuous centrifugal spread. Histologically there is a subclinical, iceberg-like growth pattern. Like keratoacanthoma, KCM is a highly differentiated, biologically benign, non-metastasizing tumour. The treatment of choice is early excision of the tumour.
离心性边缘性角化棘皮瘤(KCM)是一种罕见的、独特的角化棘皮瘤变体。基于三项个人观察及文献回顾,作者描述了该肿瘤的临床和组织学特征。临床上,KCM的特点是缺乏自发缓解倾向且呈持续性离心性扩散。组织学上,存在一种亚临床的、冰山样生长模式。与角化棘皮瘤一样,KCM是一种高分化、生物学行为良性、不转移的肿瘤。首选治疗方法是早期切除肿瘤。