Yuge Sayuri, Godoy Deise Aparecida Santos, Melo Maria Carolina Coelho de, Sousa Danilo Silveira, Soares Cleverson Teixeira
Department of Dermatology, Instituto Lauro de Souza Lima, São Paulo, Brazil.
J Am Acad Dermatol. 2006 May;54(5 Suppl):S218-9. doi: 10.1016/j.jaad.2005.07.023.
Keratoacanthoma centrifugum marginatum (KCM) is a rare variant of keratoacanthoma, characterized by progressive peripheral growth with concomitant healing of the central area of the tumor. We present a patient with KCM who was treated with topical 5% 5-fluorouracil. This is the third reported case of KCM treated with this agent.
离心性边缘性角化棘皮瘤（KCM）是角化棘皮瘤的一种罕见变体，其特征为肿瘤外周呈进行性生长，同时肿瘤中心区域愈合。我们报告了一例接受外用5% 5-氟尿嘧啶治疗的KCM患者。这是第三例报道使用该药物治疗的KCM病例。
