Watanabe D, Tachi N, Tomita Y
Department of Dermatology, Nagoya University School of Medicine, Japan.
J Dermatol. 1999 Aug;26(8):541-3. doi: 10.1111/j.1346-8138.1999.tb02044.x.
Among the variants of solitary keratoacanthoma, keratoacanthoma centrifugum marginatum (KCM) is characterized by the lack of a tendency toward spontaneous remission and by continuous centrifugal spread. We describe a case of KCM arising from the scar after an old skin injury. The lesion appeared on the dorsum of the right hand, grew peripherally for 30 months, and became a tumor with a multinodular margin and central atrophy. A biopsy specimen from the edge of the tumor showed features resembling typical solitary keratoacanthoma.
在孤立性角化棘皮瘤的各种变体中,离心性边缘性角化棘皮瘤(KCM)的特点是缺乏自发缓解的倾向且呈持续离心性扩散。我们描述了一例起源于陈旧性皮肤损伤后瘢痕的KCM病例。病变出现在右手背部,向周边生长30个月,形成一个边缘呈多结节状且中央萎缩的肿瘤。取自肿瘤边缘的活检标本显示出类似典型孤立性角化棘皮瘤的特征。