Chirwa M, Mulwafu W, Aswani J M, Masinde P W, Mkakosya R, Soko D
ENT Department, Kamuzu Central Hospital, Lilongwe, Malawi.
College of Medicine, Univeristy of Malawi and Queen Elizabeth Central Hospital, Blantyre, Malawi.
Malawi Med J. 2015 Dec;27(4):120-4.
Chronic suppurative otitis media (CSOM) is still a significant health problem in developing countries. Therefore, it was pertinent to determine the local Malawian microbiology in order to guide adequate treatment, avoid complications, and provide records for future reference.
The study sought to determine the CSOM-causing microorganisms at Queen Elizabeth Central Hospital in Blantyre, Malawi, and establish their relationship signs and symptoms, and with the demographic pattern of the study.
This was a hospital-based cross-sectional descriptive study carried out at the ENT outpatient clinic and the Microbiology Department of Queen Elizabeth Central Hospital.The sample comprised 104 patients with unilateral or bilateral active CSOM, who met the inclusion criteria. All patients were evaluated through a detailed history and clinical examination. Pus samples from draining ears were collected by aspiration with a sterile pipette. The specimens were immediately sent for microbiological analysis. Data were analyzed using SPSS.version 20.
The study found that Proteus mirabilis, Pseudomonas aeruginosa, and Staphylococcus aureus were the most prevalent aerobic bacteria, while Bacteroides spp. and Peptostreptococcus spp. were the commonest anaerobic bacteria causing CSOM. These CSOM-causing microorganisms were predominant among males aged 18 years and below. Some CSOM-causing microorganisms were-significantly more so than the others-characteristically associated with each of the following clinical features: quantity of pus drainage, mode of onset, otalgia, hearing loss, location of tympanic membrane perforation, and mucosal appearance.
慢性化脓性中耳炎（CSOM）在发展中国家仍是一个重大的健康问题。因此，确定马拉维当地的微生物情况对于指导适当治疗、避免并发症以及提供未来参考记录具有重要意义。
本研究旨在确定马拉维布兰太尔伊丽莎白女王中央医院引起CSOM的微生物，并确定它们与体征和症状以及研究人群特征模式之间的关系。
这是一项基于医院的横断面描述性研究，在伊丽莎白女王中央医院的耳鼻喉科门诊和微生物科进行。样本包括104例符合纳入标准的单侧或双侧活动性CSOM患者。所有患者均通过详细的病史和临床检查进行评估。用无菌移液器从引流耳中采集脓液样本。标本立即送去进行微生物分析。使用SPSS 20.0版软件进行数据分析。
研究发现，奇异变形杆菌、铜绿假单胞菌和金黄色葡萄球菌是最常见的需氧菌，而拟杆菌属和消化链球菌属是引起CSOM最常见的厌氧菌。这些引起CSOM的微生物在18岁及以下男性中占主导地位。一些引起CSOM的微生物与以下每种临床特征的关联性明显高于其他微生物：脓液引流的量、发病方式、耳痛、听力损失、鼓膜穿孔的位置以及黏膜外观。
