Antonio-Santos Aileen A, Murad-Kejbou Sally J, Foroozan Rod, Yedavally Sunita, Kaufman David I, Eggenberger Eric R
J Vasc Interv Neurol. 2016 Jan;8(5):17-21.
To evaluate the prevalence and clinical profile of patients with biopsy-proven arteritic anterior ischemic optic neuropathy presenting with preserved visual acuity of 20/40 or better and those with an initial poor visual acuity of 20/50 or worse through a retrospective chart review.
Nine of 37 patients with arteritic anterior ischemic optic neuropathy presented with a preserved visual acuity of 20/40 or better in the affected eye. All patients with preserved visual acuity had initial visual field defects that spared the central field. All 37 patients immediately received high-dose corticosteroid therapy. Visual acuity worsened by > 2 lines in one of nine patients (11%) with preserved visual acuity, with a corresponding progression of visual field constriction.
Although preserved visual acuity of 20/40 or better has traditionally been associated with the nonarteritic form of anterior ischemic optic neuropathy, giant cell arteritis should still be strongly considered, especially if they have giant cell arteritis systemic symptoms.
通过回顾性病历审查,评估经活检证实的动脉炎性前部缺血性视神经病变患者中,患眼视力保持在20/40或更好的患者以及初始视力较差(20/50或更差)的患者的患病率和临床特征。
37例动脉炎性前部缺血性视神经病变患者中,有9例患眼视力保持在20/40或更好。所有视力保持良好的患者最初的视野缺损均未累及中心视野。所有37例患者均立即接受了大剂量皮质类固醇治疗。9例视力保持良好的患者中有1例(11%)视力恶化超过2行,同时视野缩小相应进展。
尽管传统上认为视力保持在20/40或更好与非动脉炎性前部缺血性视神经病变有关,但仍应高度怀疑巨细胞动脉炎,尤其是那些伴有巨细胞动脉炎全身症状的患者。