Carrilho Flair J, Mattos Angelo Alves de, Vianey Alex F, Vezozzo Denise Cerqueira P, Marinho Fábio, Souto Francisco J, Cotrim Helma P, Coelho Henrique Sergio M, Silva Ivonete, Garcia José Huygens P, Kikuchi Luciana, Lofego Patricia, Andraus Wellington, Strauss Edna, Silva Giovanni, Altikes Isaac, Medeiros Jose Eymard, Bittencourt Paulo L, Parise Edison R
Faculdade de Medicina, Universidade de São Paulo, SP, Brazil.
Universidade Federal de Ciências da Saúde de Porto Alegre, RS, Brazil.
Arq Gastroenterol. 2015 Dec;52 Suppl 1:2-14. doi: 10.1590/S0004-28032015000500001.
Hepatocellular carcinoma is a malignancy of global importance and is associated with a high rate of mortality. Recent advances in the diagnosis and treatment of this disease make it imperative to update the recommendations on the management of the disease. In order to draw evidence-based recommendations concering the diagnosis and management of hepatocellular carcinoma, the Brazilian Society of Hepatology has sponsored a single-topic meeting in João Pessoa (PB). All the invited pannelists were asked to make a systematic review of the literature and to present topics related to the risk factors for its development, methods of screening, radiological diagnosis, staging systems, curative and palliative treatments and hepatocellular carcinoma in noncirrhotic liver. After the meeting, all panelists gathered together for the discussion of the topics and the elaboration of those recommendations. The text was subsequently submitted for suggestions and approval of all members of the Brazilian Society of Hepatology through its homepage. The present paper is the final version of the reviewed manuscript containing the recommendations of the Brazilian Society of Hepatology.
肝细胞癌是一种具有全球重要性的恶性肿瘤,且死亡率很高。该疾病诊断和治疗方面的最新进展使得更新其管理建议变得势在必行。为了得出关于肝细胞癌诊断和管理的循证建议,巴西肝病学会在若昂佩索阿(帕拉伊巴州)主办了一次专题会议。所有受邀的小组成员都被要求对文献进行系统回顾,并介绍与其发生的风险因素、筛查方法、放射学诊断、分期系统、根治性和姑息性治疗以及非肝硬化肝脏中的肝细胞癌相关的主题。会议结束后,所有小组成员聚集在一起讨论这些主题并拟定这些建议。随后,该文本通过巴西肝病学会的主页提交给所有成员征求意见并获得批准。本文是经过审阅的手稿的最终版本,其中包含巴西肝病学会的建议。