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腹腔镜下将失败的可调节胃束带术转换为袖状胃切除术的一两个步骤:一项针对3357例病态肥胖患者的法国全国性研究

One or two steps for laparoscopic conversion of failed adjustable gastric banding to sleeve gastrectomy: a nationwide French study on 3357 morbidly obese patients.

作者信息

Schneck Anne-Sophie, Lazzati Andrea, Audureau Etienne, Hemery François, Gugenheim Jean, Azoulay Daniel, Iannelli Antonio

机构信息

Centre Hospitalier Universitaire de Nice, Digestive Center, Nice, France and University of Nice-Sophia-Antipolis, Faculty of Medecine, Nice, France.

Department of Digestive Surgery, Centre Hospitalier Intercommunal de Créteil, Créteil, France.

出版信息

Surg Obes Relat Dis. 2016 May;12(4):840-848. doi: 10.1016/j.soard.2015.10.070. Epub 2015 Oct 21.

Abstract

BACKGROUND

Adjustable gastric banding (AGB) has been a very common bariatric procedure, but long-term AGB related complications have led to an increased number of second procedures. Sleeve gastrectomy (SG) is one option and can be done as a 1- or 2-step procedure.

OBJECTIVES

To compare the 1-step and 2-step approachs of conversion of AGB to SG with respect to postoperative mortality and morbidity.

SETTING

Nationwide study, France.

METHODS

All morbidly obese patients who underwent AGB followed by SG in France between 2007 and 2012 were included. Multivariate analyses were conducted using the French National Health Service Database data to ascertain predictive factors for 90-day postoperative mortality and morbidity.

RESULTS

There were 2061 and 1296 patients in the 1-step and 2-step conversion groups, respectively. The readmission rate was 22.8% and 16.5% in the 1- and 2-step groups, respectively (P<.001). More patients required an intensive care unit stay in the 1-step group (11.7 % versus 6.7%; P<.001). The 90-day mortality was .1%, with no difference between the 2 groups (1% versus .08%). The complication rate was 14.7% (1-step 15.9% versus 2-step 12.7%; P = .009). The timing of AGB removal (P = .02), patient age 50-60 years (P = .004), hypertension (P = .01), surgical approach (P = .002), and hospital status (P = .015) were significantly associated with the complication rate.

CONCLUSION

This study indicates that the 2-step conversion of failed AGB to SG results in a significantly reduced rate of postoperative staple line leaks, gastric tube stricture, respiratory complication, and need for intensive care unit stay.

摘要

背景

可调节胃束带术(AGB)一直是一种非常常见的减肥手术,但与AGB相关的长期并发症导致二次手术的数量增加。袖状胃切除术(SG)是一种选择,可以作为一期或二期手术进行。

目的

比较AGB转为SG的一期和二期手术方法在术后死亡率和发病率方面的差异。

设置

法国全国性研究。

方法

纳入2007年至2012年期间在法国接受AGB后再行SG的所有病态肥胖患者。使用法国国家卫生服务数据库数据进行多变量分析,以确定术后90天死亡率和发病率的预测因素。

结果

一期和二期转换组分别有2061例和1296例患者。一期和二期组的再入院率分别为22.8%和16.5%(P<0.001)。一期组更多患者需要入住重症监护病房(11.7%对6.7%;P<0.001)。90天死亡率为0.1%,两组之间无差异(1%对0.08%)。并发症发生率为14.7%(一期15.9%对二期12.7%;P = 0.009)。AGB移除时间(P = 0.02)、患者年龄50 - 60岁(P = 0.004)、高血压(P = 0.01)、手术方式(P = 0.002)和医院状态(P = 0.015)与并发症发生率显著相关。

结论

本研究表明,失败的AGB转为SG的二期手术可显著降低术后吻合口漏、胃管狭窄、呼吸并发症以及入住重症监护病房的需求发生率。

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