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腹腔镜袖状胃切除术治疗胃旁路术后失败:真的有效吗?六年随访。

Laparoscopic sleeve gastrectomy after failed gastric banding: is it really effective? Six years of follow-up.

机构信息

Assistance Publique-Hôpitaux de Paris (AP-HP), Department of Digestive and Metabolic Surgery, Avicenne University Hospital. Centre Intégré Nord Francilien de la Prise en Charge de l'Obésité (CINFO). Université Paris XIII-UFR SMBH "Léonard de Vinci", AP-HP, Bobigny, France; Department of General and Bariatric Surgery, Clinique Bouchard, Marseille, France.

Assistance Publique-Hôpitaux de Paris (AP-HP), Department of Digestive and Hepato-Pancreato-Biliary Surgery, Liver Transplantation, Pitié-Salpêtrière University Hospital, Pierre & Marie Curie University, Paris, France.

出版信息

Surg Obes Relat Dis. 2017 Jul;13(7):1165-1173. doi: 10.1016/j.soard.2017.02.008. Epub 2017 Feb 17.

Abstract

BACKGROUND

Laparoscopic sleeve gastrectomy (LSG) has become a valuable surgical option to rescue laparoscopic adjustable gastric banding (LAGB) failures.

OBJECTIVES

The aim of this study was to determine whether conversion to LSG after failed LAGB (CLSG) is a well-tolerated and effective rescue procedure compared with primary LSG (PLSG) in the long term.

SETTING

University hospital, France.

METHODS

A retrospective review of data concerning consecutive patients receiving a LSG between February 2008 and December 2014 was conducted. Mortality, postoperative complications, and weight loss outcomes were analyzed.

RESULTS

Of 701 LSG, 601 (85.7%) were PLSG and 100 (14.3%) were CLSG. The mortality rate was 0%. Overall morbidity was comparable between the primary and conversion group (10% versus 6%, P = .27). The mean percentage of excess weight loss at 3, 36, and 72 months was 34.9%, 72.1%, and 57.2% after PLSG and 22.6%, 51.2% and 29.8% after CLSG (P<.05). The failure rate (mean percentage of excess weight loss<50%) was higher in the CLSG group during the first 5 postoperative years (P < .001) with more than two thirds of the CLSG considered as having failed at 60 months. Patients who underwent band ablation as a result of insufficient weight loss or weight regain presented the worst results after conversion to LSG.

CONCLUSION

In this study, the conversion of failed LAGB to LSG in 2 steps indicated a safety profile comparable to that of primary LSG but was significantly less effective from the early postoperative course (3 mo) up to 6 years postoperatively. CLSG may not be the best option because a third operation may be needed as a result of insufficient weight loss.

摘要

背景

腹腔镜袖状胃切除术(LSG)已成为一种有价值的手术选择,可以挽救腹腔镜可调胃束带术(LAGB)失败。

目的

本研究旨在确定与原发性 LSG(PLSG)相比,LAGB 失败后转为 LSG(CLSG)是否是一种长期耐受且有效的挽救手术。

设置

法国大学医院。

方法

对 2008 年 2 月至 2014 年 12 月期间连续接受 LSG 的患者数据进行回顾性分析。分析死亡率、术后并发症和减重效果。

结果

701 例 LSG 中,601 例(85.7%)为 PLSG,100 例(14.3%)为 CLSG。死亡率为 0%。总体发病率在原发性和转换组之间无差异(10%对 6%,P =.27)。PLSG 和 CLSG 组术后 3、36 和 72 个月时的超重体重减轻百分比分别为 34.9%、72.1%和 57.2%和 22.6%、51.2%和 29.8%(P<.05)。CLSG 组在术后 5 年内的失败率(超重体重减轻百分比<50%)较高(P<.001),60 个月时超过三分之二的 CLSG 被认为失败。由于减重不足或体重反弹而行带消融术的患者,在转为 LSG 后减重效果最差。

结论

在这项研究中,2 步法将失败的 LAGB 转换为 LSG 表明其安全性与 PLSG 相当,但从术后早期(3 个月)到术后 6 年,效果明显较差。CLSG 可能不是最佳选择,因为可能需要进行第三次手术,因为减重不足。

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