Hamilton D F, Giesinger J M, MacDonald D J, Simpson A H R W, Howie C R, Giesinger K
Department of Orthopaedics, University of Edinburgh, FU413, Chancellor's Building, 49 Little France Crescent, Edinburgh, EH164SB, UK.
Department of Psychiatry and Psychotherapy, Innsbruck Medical University, Anichstrasse 35, 6020 Innsbruck, Austria.
Bone Joint Res. 2016 Mar;5(3):87-91. doi: 10.1302/2046-3758.53.2000480.
To assess the responsiveness and ceiling/floor effects of the Forgotten Joint Score -12 and to compare these with that of the more widely used Oxford Hip Score (OHS) in patients six and 12 months after primary total hip arthroplasty.
We prospectively collected data at six and 12 months following total hip arthroplasty from 193 patients undergoing surgery at a single centre. Ceiling effects are outlined with frequencies for patients obtaining the lowest or highest possible score. Change over time from six months to 12 months post-surgery is reported as effect size (Cohen's d).
The mean OHS improved from 40.3 (sd 7.9) at six months to 41.9 (sd 7.2) at 12 months. The mean FJS-12 improved from 56.8 (sd 30.1) at six months to 62.1 (sd 29.0) at 12 months. At six months, 15.5% of patients reached the best possible score (48 points) on the OHS and 8.3% obtained the best score (100 points) on the FJS-12. At 12 months, this percentage increased to 20.8% for the OHS and to 10.4% for the FJS-12. In terms of the effect size (Cohen's d), the change was d = 0.10 for the OHS and d = 0.17 for the FJS-12.
The FJS-12 is more responsive to change between six and 12 months following total hip arthroplasty than is the OHS, with the measured ceiling effect for the OHS twice that of the FJS-12. The difference in effect size of change results in substantial differences in required sample size if aiming to detect change between these two time points. This has important implications for powering clinical trials with patient-reported measures as the primary outcome.Cite this article: Dr D. F. Hamilton. Responsiveness and ceiling effects of the Forgotten Joint Score-12 following total hip arthroplasty. Bone Joint Res 2016;5:87-91. DOI: 10.1302/2046-3758.53.2000480.
评估遗忘关节评分-12（Forgotten Joint Score -12，FJS-12）的反应度及天花板/地板效应，并将其与更广泛使用的牛津髋关节评分（Oxford Hip Score，OHS）在初次全髋关节置换术后6个月和12个月的患者中的情况进行比较。
我们前瞻性收集了在单一中心接受手术的193例患者全髋关节置换术后6个月和12个月的数据。通过获得最低或最高可能分数的患者频率来概述天花板效应。手术6个月至12个月期间随时间的变化以效应量（Cohen's d）报告。
OHS的均值从6个月时的40.3（标准差7.9）提高到12个月时的41.9（标准差7.2）。FJS-12的均值从6个月时的56.8（标准差30.1）提高到12个月时的62.1（标准差29.0）。6个月时，15.5%的患者在OHS上达到最佳可能分数（48分），8.3%的患者在FJS-12上获得最佳分数（100分）。12个月时,OHS的这一百分比增至20.8%，FJS-12的这一百分比增至10.4%。就效应量（Cohen's d）而言，OHS的变化为d = 0.10，FJS-12的变化为d = 0.17。
全髋关节置换术后6至12个月期间，FJS-12比OHS对变化更敏感，OHS测得的天花板效应是FJS-12的两倍。如果旨在检测这两个时间点之间的变化，效应量变化的差异会导致所需样本量存在实质性差异。这对于以患者报告的测量结果作为主要结局的临床试验效能具有重要意义。引用本文：D. F. 汉密尔顿博士。全髋关节置换术后遗忘关节评分-12的反应度和天花板效应。《骨与关节研究》2016；5：87 - 91。DOI：10.1302/2046 - 3758.53.2000480。
